Cellular and Molecular Determinants of Biologic Drugs Resistance and Therapeutic Failure in Inflammatory Bowel Disease
P Puca, I Capobianco, G Coppola… - International Journal of …, 2024 - mdpi.com
The advent of biologic drugs has revolutionized the treatment of Inflammatory Bowel
Disease, increasing rates of response and mucosal healing in comparison to conventional …
Disease, increasing rates of response and mucosal healing in comparison to conventional …
Mitochondrial dysfunction: unraveling the elusive biology behind anti-TNF response during ulcerative colitis
D Kioroglou, A Peña-Cearra, A Corraliza, I Seoane… - bioRxiv, 2024 - biorxiv.org
Background: Recent studies hint at mitochondrial genes influencing UC patient response to
anti-TNF treatment. We evaluated this hypothesis by following a targeted strategy to identify …
anti-TNF treatment. We evaluated this hypothesis by following a targeted strategy to identify …
Stress triggers gut dysbiosis via CRF-CRHR1-mitochondria pathway
L Duan - 2024 - researchsquare.com
Psychological stress can lead to gut dysbiosis, yet the precise mechanisms underlying the
transfer of stress signals from the brain to the gut remain elusive. Here we describe a new …
transfer of stress signals from the brain to the gut remain elusive. Here we describe a new …