[HTML][HTML] Pathophysiological mechanisms of thrombosis in acute and long COVID-19

H Jing, X Wu, M Xiang, L Liu, VA Novakovic… - Frontiers in …, 2022 - frontiersin.org
COVID-19 patients have a high incidence of thrombosis, and thromboembolic complications
are associated with severe COVID-19 and high mortality. COVID-19 disease is associated …

[HTML][HTML] Pathogenesis and treatment of cytokine storm induced by infectious diseases

XD Tang, TT Ji, JR Dong, H Feng, FQ Chen… - International journal of …, 2021 - mdpi.com
Cytokine storm is a phenomenon characterized by strong elevated circulating cytokines that
most often occur after an overreactive immune system is activated by an acute systemic …

[HTML][HTML] The role of IL-1 family of cytokines and receptors in pathogenesis of COVID-19

S Makaremi, A Asgarzadeh, H Kianfar… - Inflammation …, 2022 - Springer
A global pandemic has erupted as a result of the new brand coronavirus, severe acute
respiratory syndrome coronavirus 2 (SARS-CoV-2). This pandemic has been consociated …

Current evidence on the use of anakinra in COVID-19

E Khani, M Shahrabi, H Rezaei, F Pourkarim… - International …, 2022 - Elsevier
Despite the progressing knowledge in COVID-19 management, remdesivir is the only agent
that got approval to inhibit viral replication. However, there are limited data about effective …

[HTML][HTML] Invasive pulmonary aspergillosis associated with viral pneumonitis

IMW Dewi, NAF Janssen, D Rosati, M Bruno… - Current opinion in …, 2021 - Elsevier
Highlights•Invasive pulmonary aspergillosis (IPA) can complicate severe influenza and
coronavirus disease 2019 (COVID-19).•IAPA and CAPA pathogenesis share features such …

Anakinra in hospitalized non-intubated patients with coronavirus disease 2019: a systematic review and meta-analysis

F Barkas, S Filippas-Ntekouan, M Kosmidou… - …, 2021 - academic.oup.com
Objectives Acute respiratory distress syndrome and cytokine release syndrome are the
major complications of coronavirus disease 2019 (COVID-19) associated with increased …

[HTML][HTML] Specific interleukin-1 inhibitors, specific interleukin-6 inhibitors, and GM-CSF blockades for COVID-19 (at the edge of sepsis): a systematic review

Y Wang, K Zhu, R Dai, R Li, M Li, X Lv… - Frontiers in …, 2022 - frontiersin.org
Sepsis is a syndrome with high mortality, which seriously threatens human health. During
the pandemic of coronavirus disease 2019 (COVID-19), some severe and critically ill COVID …

[HTML][HTML] Current treatment strategies for COVID‑19

F Han, Y Liu, M Mo, J Chen… - Molecular …, 2021 - spandidos-publications.com
The spread of the novel severe acute respiratory syndrome coronavirus 2 (SARS‑CoV‑2)
emerged suddenly at the end of 2019 and the disease came to be known as coronavirus …

A randomized controlled clinical trial on efficacy and safety of anakinra in patients with severe COVID‐19

AB Kharazmi, O Moradi, M Haghighi… - Immunity …, 2022 - Wiley Online Library
Introduction Hyperinflammatory state has a role in the pathogenesis of COVID‐19. Anakinra
could reduce inflammation and help to combat the condition. In this study, we aimed to …

[HTML][HTML] Inhibition of Toll-like receptor 4 and Interleukin-1 receptor prevent SARS-CoV-2 mediated kidney injury

D Nakazawa, Y Takeda, M Kanda, U Tomaru… - Cell Death …, 2023 - nature.com
Acute kidney injury (AKI) is a common and severe complication of the coronavirus disease
2019 (COVID-19). Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) directly …