Autologous human mesenchymal stem cell-based therapy in infertility: New strategies and future perspectives

ZB Mohamed Rasheed, F Nordin… - Biology, 2023 - mdpi.com
Simple Summary Infertility is a global issue and the currently available treatments for
infertility are known to pose some risks and are lacking in solving infertility problems that are …

Quantitative haplotype-resolved analysis of mitochondrial DNA heteroplasmy in Human single oocytes, blastoids, and pluripotent stem cells

C Bi, L Wang, Y Fan, B Yuan, S Alsolami… - Nucleic Acids …, 2023 - academic.oup.com
Maternal mitochondria are the sole source of mtDNA for every cell of the offspring.
Heteroplasmic mtDNA mutations inherited from the oocyte are a common cause of metabolic …

[HTML][HTML] Astragaloside IV protects against ischemia/reperfusion (I/R)-induced kidney injury based on the Keap1-Nrf2/ARE signaling pathway

Y Su, J Xu, S Chen, J Feng, J Li, Z Lei… - Translational …, 2022 - ncbi.nlm.nih.gov
Background This study sought to investigate the protective effects of Astragaloside IV (AS-IV)
on ischemia-reperfusion (I/R) renal injury based on the keap1-Nrf2/ARE signaling pathway …

Differential expression profiles and potential intergenerational functions of tRNA-derived small RNAs in mice after cadmium exposure

L Zeng, J Zhou, Y Zhang, X Wang, M Wang… - Frontiers in Cell and …, 2022 - frontiersin.org
Cadmium (Cd) is a toxic heavy metal and ubiquitous environmental endocrine disruptor.
Previous studies on Cd-induced damage to male fertility mainly focus on the structure and …

Knock out of specific maternal vitellogenins in zebrafish (Danio rerio) evokes vital changes in egg proteomic profiles that resemble the phenotype of poor quality eggs

O Yilmaz, A Patinote, E Com, C Pineau, J Bobe - BMC genomics, 2021 - Springer
Background We previously reported the results of CRISPR/Cas9 knock-out (KO) of type-I
and type-III vitellogenins (Vtgs) in zebrafish, which provided the first experimental evidence …

Single-cell individual complete mtDNA sequencing uncovers hidden mitochondrial heterogeneity in human and mouse oocytes

C Bi, L Wang, Y Fan, G Ramos-Mandujano, B Yuan… - bioRxiv, 2020 - biorxiv.org
The ontogeny and dynamics of mtDNA heteroplasmy remain unclear due to limitations of
current mtDNA sequencing methods. We developed individual Mi tochondrial G enome seq …

Making mitochondrial haplogroup and DNA sequence predictions from low-density genotyping data

ELE Drummond - 2021 - search.proquest.com
The mitochondrial genome (mtDNA) is inherited differently and mutates more frequently than
the genetic material residing in the cells' nucleus. Whilst the genome of the mtDNA is small …

Türk toplumunda benign ve malign tiroit nodüllerinde mitokondriyal dna sık delesyon prevalansının belirlenmesi

N Apaydın - 2021 - acikerisim.nku.edu.tr
mtDNA mutasyonlarının veya varyasyonlarının birçok multifaktöryel hastalıkta ve yaşlanma
süreçlerinde rol oynadığına dair bilgi literatürde yer almaktadır. Literatürde 4977 baz çiftlik …

[PDF][PDF] Knock out of Specific Maternal Vitellogenins in Zebrafish (Danio Rerio) Evokes Vital Changes in Egg Proteomic Pro les that resemble the Phenotype of Poor …

O YILMAZ, A Patinote, E Com, C Pineau, J Bobe - scholar.archive.org
Background We previously reported the results of CRISPR/Cas9 knock-out (KO) of type-I
and type-III vitellogenins (Vtgs) in zebra sh, which provided the rst experimental evidence of …

Compositions and methods of labeling mitochondrial nucleic acids and sequencing and analysis thereof

M Li, C Bi - US Patent App. 17/409,731, 2022 - Google Patents
2023-01-12 Assigned to KING ABDULLAH UNIVERSITY OF SCIENCE AND TECHNOLOGY
reassignment KING ABDULLAH UNIVERSITY OF SCIENCE AND TECHNOLOGY …