BRAF mutational status as a prognostic marker for survival in malignant melanoma: a systematic review and meta-analysis
L Ny, M Hernberg, M Nyakas, J Koivunen… - Acta …, 2020 - Taylor & Francis
Background: The analysis of the BRAF mutational status has been established as a
standard procedure during diagnosis of advanced malignant melanoma due to the fact that …
standard procedure during diagnosis of advanced malignant melanoma due to the fact that …
[PDF][PDF] Signaling pathways downstream to receptor tyrosine kinases: Targets for cancer treatment
E Cordover, A Minden, S Lehman, O Zhao - J. Cancer Metastasis Treat, 2020 - f.oaes.cc
Mammalian cells have the ability to respond to a myriad of diverse extracellular stimuli that
modulate cell function. This often involves ligands binding to cell surface receptors and …
modulate cell function. This often involves ligands binding to cell surface receptors and …
MAPK Pathway and TERT Promoter Gene Mutation Pattern and Its Prognostic Value in Melanoma Patients: A Retrospective Study of 2,793 Cases
X Bai, Y Kong, Z Chi, X Sheng, C Cui, X Wang… - Clinical Cancer …, 2017 - AACR
Purpose: Ethnic differences are conspicuous in melanoma. This study is to obtain a
comprehensive view of a genomic landscape and a better understanding of the correlations …
comprehensive view of a genomic landscape and a better understanding of the correlations …
[HTML][HTML] Genistein inhibits the growth and regulates the migration and invasion abilities of melanoma cells via the FAK/paxillin and MAPK pathways
S Cui, J Wang, Q Wu, J Qian, C Yang, P Bo - Oncotarget, 2017 - ncbi.nlm.nih.gov
Genistein is one of the main components of soy-based foods, which are widely known for
their many benefits, including anti-cancer, anti-inflammatory, and antioxidant effects. In this …
their many benefits, including anti-cancer, anti-inflammatory, and antioxidant effects. In this …
[HTML][HTML] A six-long non-coding RNA signature predicts prognosis in melanoma patients
S Yang, J Xu, X Zeng - International journal of oncology, 2018 - spandidos-publications.com
The aim of this study was to identify long non-coding RNAs (lncRNAs) which may prove
useful for risk-classifying patients with melanoma. For this purpose, based on a dataset from …
useful for risk-classifying patients with melanoma. For this purpose, based on a dataset from …
[HTML][HTML] Extracellular heat shock protein 70 promotes osteogenesis of human mesenchymal stem cells through activation of the ERK signaling pathway
E Chen, D Xue, W Zhang, F Lin, Z Pan - FEBS letters, 2015 - Elsevier
Heat shock proteins have protective effects when cells are exposed to stress. However, the
relationship between extracellular heat shock protein 70 (eHSP70) and osteogenesis of …
relationship between extracellular heat shock protein 70 (eHSP70) and osteogenesis of …
Quercetin inhibits LPS-induced macrophage migration by suppressing the iNOS/FAK/paxillin pathway and modulating the cytoskeleton
S Cui, Q Wu, J Wang, M Li, J Qian, S Li - Cell Adhesion & Migration, 2019 - Taylor & Francis
The natural flavonoid quercetin has antioxidant, anti-inflammatory, and anticancer effects.
We investigated the effect of quercetin on lipopolysaccharide (LPS)-induced macrophage …
We investigated the effect of quercetin on lipopolysaccharide (LPS)-induced macrophage …
[HTML][HTML] The Droplet Digital PCR: A New Valid Molecular Approach for the Assessment of B-RAF V600E Mutation in Hairy Cell Leukemia
F Guerrini, M Paolicchi, F Ghio, E Ciabatti… - Frontiers in …, 2016 - frontiersin.org
Hairy cell leukemia (HCL) is a chronic lymphoproliferative B-cell disorder where the B-RAF
V600E mutation has been recently detected, as reported for solid neoplasias but not for …
V600E mutation has been recently detected, as reported for solid neoplasias but not for …
[HTML][HTML] Crosstalk between p38 and Erk 1/2 in downregulation of FGF1-induced signaling
M Zakrzewska, L Opalinski, EM Haugsten… - International journal of …, 2019 - mdpi.com
Mitogen-activated protein kinases (MAPK): Erk1 and Erk2 are key players in negative-
feedback regulation of fibroblast growth factor (FGF) signaling. Upon activation, Erk1 and …
feedback regulation of fibroblast growth factor (FGF) signaling. Upon activation, Erk1 and …
Extranodal spread is associated with recurrence and poor survival in stage III cutaneous melanoma patients
TR Crookes, RA Scolyer, S Lo, M Drummond… - Annals of surgical …, 2017 - Springer
Background Inconsistent data suggests extranodal spread (ENS) is an adverse prognostic
factor in Stage III melanoma patients but it remains contentious. By rigorously matching …
factor in Stage III melanoma patients but it remains contentious. By rigorously matching …