Despite effective antiretroviral therapy (ART), people living with HIV (PLWH) still present
persistent chronic immune activation and inflammation. This condition is the result of several …

HIV infection has transitioned from an acute, fatal disease to a chronic one managed by
antiretroviral therapy. Thus, the aging population of people living with HIV (PLWH) continues …

Background Emerging evidence argues that monocytes, circulating innate immune cells, are
principal players in COVID-19 pneumonia. The study aimed to investigate the role of soluble …

Background. Monocytes and monocyte-derived macrophages promote atherosclerosis
through increased inflammation and vascular remodeling. This may be especially true in …

Chronic inflammation and T cell dysregulation persist in individuals infected with human
immunodeficiency virus type 1 (HIV-1), even after successful antiretroviral treatment. The …

One-third of people with HIV in sub-Saharan Africa start antiretroviral therapy (ART) with
advanced disease. We investigated associations between immune biomarkers and mortality …

Objective: Persistent immune activation is thought to contribute to increased cardiovascular
disease risk in HIV and statins may help modulate systemic immune activation. We aimed to …

BACKGROUND Identifying factors that predict the timing of HIV rebound after treatment
interruption will be crucial for designing and evaluating interventions for HIV remission …

Even after attainment of sustained viral suppression following implementation of highly
active antiretroviral therapy, HIV-infected persons continue to experience persistent, low …

People infected with severe acute respiratory syndrome coronavirus 2 display a wide range
of illness, from asymptomatic infection to severe respiratory distress resulting in death. We …