A raising dawn of pentoxifylline in management of inflammatory disorders in Covid-19

G Mostafa-Hedeab, HM Al-Kuraishy, AI Al-Gareeb… - …, 2022 - Springer
The existing pandemic viral infection caused by severe acute respiratory syndrome
coronavirus type 2 (SARS-CoV-2) leads to coronavirus disease 2019 (Covid-19). SARS …

Possible beneficial actions of caffeine in SARS-CoV-2

BS Romero-Martinez, LM Montano… - International Journal of …, 2021 - mdpi.com
The COVID-19 pandemic has established an unparalleled necessity to rapidly find effective
treatments for the illness; unfortunately, no specific treatment has been found yet. As this is a …

Computational methods directed towards drug repurposing for COVID-19: advantages and limitations

PP Sharma, M Bansal, A Sethi, L Pena, VK Goel… - RSC …, 2021 - pubs.rsc.org
Novel coronavirus disease 2019 (COVID-19) has significantly altered the socio-economic
status of countries. Although vaccines are now available against the severe acute …

[HTML][HTML] Hypoxia may be a determinative factor in COVID-19 progression

P Grieb, M Swiatkiewicz, K Prus, K Rejdak - Current Research in …, 2021 - Elsevier
The disease which develops following SARS-CoV-2 virus infection, known as COVID-19, in
most affected countries displays mortality from 1.5% to 9.8%. When leukocytosis due to …

A systematic review and Bayesian network meta-analysis of medical therapies for lichen planopilaris

H Husein-ElAhmed, S Husein-ElAhmed - Dermatology, 2024 - karger.com
Background: Lichen planopilaris (LPP) is a primary chronic lymphocytic cutaneous disorder
that selectively destroys the hair follicles, resulting in scarring alopecia. Unfortunately …

Purinergic receptor ligands: the cytokine storm attenuators, potential therapeutic agents for the treatment of COVID-19

M Zarei, N Sahebi Vaighan, SA Ziai - Immunopharmacology and …, 2021 - Taylor & Francis
Abstract The coronavirus disease-19 (COVID-19), at first, was reported in Wuhan, China,
and then rapidly became pandemic throughout the world. Cytokine storm syndrome (CSS) in …

Investigating theobromine as a potential anti‐human coronaviral agent

J Li, Y Wang, S Rajpoot, M Lavrijsen… - Microbiology and …, 2023 - Wiley Online Library
Coronaviruses (CoVs) have long been known to infect humans, mainly alpha‐CoV and beta‐
CoV. The vaccines developed for SARS‐CoV‐2 are likely not effective against other …

[HTML][HTML] Impacts of Comorbidity and Mental Shock on Organic Micropollutants in Surface Water during and after the COVID-19 Pandemic in Wuhan (2019–2021) …

J Zhao, J Kang, X Cao, R Bian, G Liu, S Hu, X Wu, C Li… - Engineering, 2024 - Elsevier
The first pandemic wave of coronavirus disease 2019 (COVID-19) induced a considerable
increase in several antivirals and antibiotics in surface water. The common symptoms of …

[PDF][PDF] Xanthine: Synthetic Strategy And Biological Activity

K Yadav, D Yadav, R Yadav - Biointerface Res Appl …, 2021 - biointerfaceresearch.com
Xanthine and its derivatives belong to the class of purine alkaloids. They are natural bases
holding nitrogen atoms within the molecular structure, and they have an effective …

Immunomodulatory Effects of Pentoxifylline: Profiling Data Based on RAW 264.7 Cellular Signaling

MH Seo, MY Eo, TTH Nguyen, HJ Yang, SM Kim - Applied Sciences, 2021 - mdpi.com
Pentoxifylline (PTX) is a methylxanthine derivative that has been developed as an
immunomodulatory agent and an improvement of microcirculation. Osteoradionecrosis …