Cell differentiation, proliferation, and death are vital for immune homeostasis. Wnt signaling
plays essential roles in processes across species. The roles of Wnt signaling proteins and …

Molecular signaling pathways involved in cancer have been intensively studied due to their
crucial role in cancer cell growth and dissemination. Among them, zinc finger E-box binding …

Gastric cancer is a heterogeneous cancer, making treatment responses difficult to predict.
Here we show that we identify two distinct molecular subtypes, mesenchymal phenotype …

Identifying molecular alterations in normal tissue adjacent to cancer is important for
understanding cancer aetiology and designing preventive measures. Here we analyse the …

Wnt signaling plays key roles in many aspects of development. In this review, we will briefly
describe the components of signaling pathways induced by Wnt ligands and then describe …

Secreted frizzled-related protein 1 (SFRP1) is a gene that belongs to the secreted
glycoprotein SFRP family. SFRP1 has been classified as a tumor suppressor gene due to …

Wnt signaling refers to a conserved signaling pathway, widely studied due to its roles in
cellular communication, cell fate decisions, development and cancer. However, the exact …

Atherosclerosis, a pathology affecting large and medium-sized arteries, is the major cause of
cardiovascular morbidity/mortality in industrialized countries. During atherosclerosis, cells …

Background Glioblastoma (GBM) is the deadliest and the most common primary brain tumor
in adults. The invasiveness and proliferation of GBM cells can be decreased through the …

The rapid adoption of gene editing tools such as CRISPRs and TALENs for research and
eventually therapeutics necessitates assays that can rapidly detect and quantitate the …