Neuropharmacology of N, N-dimethyltryptamine

TM Carbonaro, MB Gatch - Brain research bulletin, 2016 - Elsevier
Abstract N, N-dimethyltryptamine (DMT) is an indole alkaloid widely found in plants and
animals. It is best known for producing brief and intense psychedelic effects when ingested …

Microbe-host interactions: structure and role of Gram-negative bacterial porins

S Galdiero, A Falanga, M Cantisani… - Current Protein and …, 2012 - ingentaconnect.com
Gram negative bacteria have evolved many mechanisms of attaching to and invading host
epithelial and immune cells. In particular, many outer membrane proteins (OMPs) are …

A possibly sigma-1 receptor mediated role of dimethyltryptamine in tissue protection, regeneration, and immunity

E Frecska, A Szabo, MJ Winkelman, LE Luna… - Journal of neural …, 2013 - Springer
Abstract N, N-dimethyltryptamine (DMT) is classified as a naturally occurring serotonergic
hallucinogen of plant origin. It has also been found in animal tissues and regarded as an …

Phase II trial of pegylated interferon alfa-2b in young patients with neurofibromatosis type 1 and unresectable plexiform neurofibromas

RI Jakacki, E Dombi, SM Steinberg, S Goldman… - Neuro …, 2017 - academic.oup.com
Background. There is no proven medical therapy for plexiform neurofibromas (PNs). We
undertook a phase II trial of pegylated interferon (PI) to evaluate response and time to …

[HTML][HTML] Metastatic type 1 gastric carcinoid: a real threat or just a myth?

S Grozinsky-Glasberg, D Thomas… - World journal of …, 2013 - ncbi.nlm.nih.gov
AIM: To describe disease characteristics and treatment modalities in a group of rare patients
with metastatic gastric carcinoid type 1 (GCA1). METHODS: Information on clinical …

IFNB1/interferon-β-induced autophagy in MCF-7 breast cancer cells counteracts its proapoptotic function

M Ambjørn, P Ejlerskov, Y Liu, M Lees, M Jäättelä… - Autophagy, 2013 - Taylor & Francis
IFNB1/interferon (IFN)-β belongs to the type I IFNs and exerts potent antiproliferative,
proapoptotic, antiangiogenic and immunemodulatory functions. Despite the beneficial …

The PPAR-γ agonist troglitazone antagonizes survival pathways induced by STAT-3 in recombinant interferon-β treated pancreatic cancer cells

G Vitale, S Zappavigna, M Marra, A Dicitore… - Biotechnology …, 2012 - Elsevier
We have previously shown that cancer cells can protect themselves from apoptosis induced
by type I interferons (IFNs) through a ras→ MAPK-mediated pathway. In addition, since IFN …

Therapeutic strategies for advanced neuroendocrine carcinomas of jejunum/ileum and pancreatic origin

CJ Auernhammer, B Göke - Gut, 2011 - gut.bmj.com
Multimodal treatment options for advanced gastroenteropancreatic neuroendocrine tumours
(NET) of jejunum/ileum and of pancreatic origin are reviewed. Current topics being …

Interleukin 18: friend or foe in cancer

G Palma, A Barbieri, S Bimonte, M Palla… - … et Biophysica Acta (BBA …, 2013 - Elsevier
In the last few years, the field of tumor immunology has significantly expanded and its
boundaries, never particularly clear, have become less distinct. Although the immune …

Influence of type‐I interferon receptor expression level on the response to type‐I interferons in human pancreatic cancer cells

S Booy, CHJ van Eijck, F Dogan… - Journal of cellular …, 2014 - Wiley Online Library
Pancreatic cancer is a highly aggressive malignancy with limited treatment options. Type‐I
interferons (eg IFN‐α/‐β) have several anti‐tumour activities. Over the past few years …