Rational design of immunomodulatory hydrogels for chronic wound healing

M Kharaziha, A Baidya, N Annabi - Advanced Materials, 2021 - Wiley Online Library
With all the advances in tissue engineering for construction of fully functional skin tissue,
complete regeneration of chronic wounds is still challenging. Since immune reaction to the …

Recent applications of immunomodulatory biomaterials for disease immunotherapy

H Dai, Q Fan, C Wang - Exploration, 2022 - Wiley Online Library
Immunotherapy is used to regulate systemic hyperactivation or hypoactivation to treat
various diseases. Biomaterial‐based immunotherapy systems can improve therapeutic …

Biological responses to physicochemical properties of biomaterial surface

M Rahmati, EA Silva, JE Reseland… - Chemical Society …, 2020 - pubs.rsc.org
Biomedical scientists use chemistry-driven processes found in nature as an inspiration to
design biomaterials as promising diagnostic tools, therapeutic solutions, or tissue …

Biomaterials: foreign bodies or tuners for the immune response?

E Mariani, G Lisignoli, RM Borzì… - International journal of …, 2019 - mdpi.com
The perspectives of regenerative medicine are still severely hampered by the host response
to biomaterial implantation, despite the robustness of technologies that hold the promise to …

Advances in biomaterials for drug delivery

OS Fenton, KN Olafson, PS Pillai… - Advanced …, 2018 - Wiley Online Library
Advances in biomaterials for drug delivery are enabling significant progress in biology and
medicine. Multidisciplinary collaborations between physical scientists, engineers, biologists …

Functional and biomimetic materials for engineering of the three-dimensional cell microenvironment

G Huang, F Li, X Zhao, Y Ma, Y Li, M Lin, G Jin… - Chemical …, 2017 - ACS Publications
The cell microenvironment has emerged as a key determinant of cell behavior and function
in development, physiology, and pathophysiology. The extracellular matrix (ECM) within the …

In situ formed reactive oxygen species–responsive scaffold with gemcitabine and checkpoint inhibitor for combination therapy

C Wang, J Wang, X Zhang, S Yu, D Wen… - Science translational …, 2018 - science.org
Patients with low-immunogenic tumors respond poorly to immune checkpoint blockade (ICB)
targeting the programmed death-1 (PD-1)/programmed death-ligand 1 (PD-L1) pathway …

Macrophages, foreign body giant cells and their response to implantable biomaterials

Z Sheikh, PJ Brooks, O Barzilay, N Fine, M Glogauer - Materials, 2015 - mdpi.com
All biomaterials, when implanted in vivo, elicit cellular and tissue responses. These
responses include the inflammatory and wound healing responses, foreign body reactions …

[HTML][HTML] Biomaterials to enhance stem cell transplantation

BN Kharbikar, P Mohindra, TA Desai - Cell Stem Cell, 2022 - cell.com
The successful transplantation of stem cells has the potential to transform regenerative
medicine approaches and open promising avenues to repair, replace, and regenerate …

Chemical strategies to boost cancer vaccines

WH Li, YM Li - Chemical reviews, 2020 - ACS Publications
Personalized cancer vaccines (PCVs) are reinvigorating vaccine strategies in cancer
immunotherapy. In contrast to adoptive T-cell therapy and checkpoint blockade, the PCV …