Precise spatiotemporal regulation of gene expression is of paramount importance for
eukaryotic development. The maternal-to-zygotic transition (MZT) during early …

A wealth of biochemical and cellular data, accumulated over several years by multiple
groups, has provided a great degree of insight into the molecular mechanisms of actions of …

Zygotic genome activation (ZGA) is a crucial step of embryonic development. So far, little is
known about the role of chromatin factors during this process. Here, we used an in vivo RNA …

To understand the function of multisubunit complexes, it is of key importance to uncover the
precise mechanisms that guide their assembly. Nascent proteins can find and bind their …

Castration-resistant prostate cancer (CRPC) is a terminal disease and the molecular
underpinnings of CRPC development need to be better understood in order to improve its …

Endothelial cell (EC), consisting of the innermost cellular layer of all types of vessels, is not
only a barrier composer but also performing multiple functions in physiological processes. It …

Filamentous fungus can produce raw-starch-degrading enzyme (RSDE) that efficiently
degrades raw starch below starch gelatinization temperature. Employment of RSDE in …

General control nonderepressible 5 protein (Gcn5) and its homologs, including p300/CBP-
associated factor (PCAF), are lysine acetyltransferases that modify both histone and non …

Cassava bacterial blight (CBB) is one of the most serious diseases in cassava production,
so it is essential to explore the underlying mechanism of immune responses. Histone …

Transcription initiation constitutes a major checkpoint in gene regulation across all living
organisms. Control of chromatin function is tightly linked to this checkpoint, which is best …