MicroRNAs in idiopathic pulmonary fibrosis

KV Pandit, J Milosevic, N Kaminski - Translational research, 2011 - Elsevier
In this review, we describe the recent advances in the understanding of the role of
microRNAs in idiopathic pulmonary fibrosis (IPF), a chronic progressive and lethal fibrotic …

IGF-1 and cardiovascular disease

Y Higashi, S Gautam, P Delafontaine… - Growth Hormone & IGF …, 2019 - Elsevier
Atherosclerosis is an inflammatory arterial pathogenic condition, which leads to ischemic
cardiovascular diseases, such as coronary artery disease and myocardial infarction, stroke …

Gene expression profiles distinguish idiopathic pulmonary fibrosis from hypersensitivity pneumonitis

M Selman, A Pardo, L Barrera, A Estrada… - American journal of …, 2006 - atsjournals.org
Rationale: Many of the interstitial lung diseases represent a diagnostic and therapeutic
challenge because their clinical and even histologic features are often nonspecific …

New mechanisms of pulmonary fibrosis

RM Strieter, B Mehrad - Chest, 2009 - Elsevier
The understanding of the pathogenesis of pulmonary fibrosis continues to evolve. The initial
hypothetical model suggested chronic inflammation as the cause of pulmonary fibrosis …

Insulin-like growth factor binding proteins 3 and 5 are overexpressed in idiopathic pulmonary fibrosis and contribute to extracellular matrix deposition

JM Pilewski, L Liu, AC Henry, AV Knauer… - The American journal of …, 2005 - Elsevier
Idiopathic pulmonary fibrosis (IPF) is a fibrotic disease of unknown etiology that results in
significant morbidity and mortality. The pathogenesis of IPF is not completely understood …

[HTML][HTML] Lung inflammation and fibrosis

PA Ward, GW Hunninghake - … journal of respiratory and critical care …, 1998 - atsjournals.org
Lung research supported by the National Heart, Lung, and Blood Institute (NHLBI) has had
important outcomes that have resulted in an infinitely better understanding of how …

Expression of growth factors and remodelling of the airway wall in bronchial asthma.

M Hoshino, Y Nakamura, JJ Sim - Thorax, 1998 - thorax.bmj.com
BACKGROUND: Bronchial asthma is characterised by airway structural changes, including
mucosal inflammatory infiltration and subepithelial collagen deposition, that may represent …

The role of circulating mesenchymal progenitor cells (fibrocytes) in the pathogenesis of pulmonary fibrosis

RM Strieter, EC Keeley, MA Hughes… - Journal of leukocyte …, 2009 - academic.oup.com
Bone marrow-derived fibrocytes review as key cellular players in the promotion of the
pathogenesis of variety of fibroproliferative disorders, including pulmonary fibrosis …

Pulmonary abnormalities in patients with primary hypogammaglobulinemia

L Kainulainen, M Varpula, K Liippo, E Svedström… - Journal of Allergy and …, 1999 - Elsevier
Background: Pulmonary complications are common in patients with primary
hypogammaglobulinemia. Intravenous immunoglobulin replacement therapy has been …

[HTML][HTML] Lung fibroblasts from patients with emphysema show markers of senescence in vitro

KC Müller, L Welker, K Paasch, B Feindt… - Respiratory …, 2006 - Springer
Background The loss of alveolar walls is a hallmark of emphysema. As fibroblasts play an
important role in the maintenance of alveolar structure, a change in fibroblast phenotype …