[HTML][HTML] Ketone bodies: from enemy to friend and guardian angel

H Kolb, K Kempf, M Röhling, M Lenzen-Schulte… - BMC medicine, 2021 - Springer
During starvation, fasting, or a diet containing little digestible carbohydrates, the circulating
insulin levels are decreased. This promotes lipolysis, and the breakdown of fat becomes the …

[HTML][HTML] Review of current evidence and clinical recommendations on the effects of low-carbohydrate and very-low-carbohydrate (including ketogenic) diets for the …

CF Kirkpatrick, JP Bolick, PM Kris-Etherton… - Journal of clinical …, 2019 - Elsevier
Abstract Historically, low-carbohydrate (CHO) and very-low-CHO diets have been used for
weight loss. Recently, these diets have been promoted for type 2 diabetes (T2D) …

[HTML][HTML] The potential health benefits of the ketogenic diet: a narrative review

K Dowis, S Banga - Nutrients, 2021 - mdpi.com
Considering the lack of a comprehensive, multi-faceted overview of the ketogenic diet (KD)
in relation to health issues, we compiled the evidence related to the use of the ketogenic diet …

Targeting aging mechanisms: pharmacological perspectives

A Moskalev, Z Guvatova, IDA Lopes, CW Beckett… - Trends in Endocrinology …, 2022 - cell.com
Geroprotectors slow down aging and promote healthy longevity in model animals. Although
hundreds of compounds have been shown to extend the life of laboratory model organisms …

[HTML][HTML] Investigating the link between ketogenic diet, NAFLD, mitochondria, and oxidative stress: a narrative review

A Paoli, G Cerullo - Antioxidants, 2023 - mdpi.com
Together with the global rise in obesity and metabolic syndrome, the prevalence of
individuals who suffer from nonalcoholic fatty liver disease (NAFLD) has risen dramatically …

[HTML][HTML] Effects of ketogenic diet on neuroinflammation in neurodegenerative diseases

Z Jiang, X Yin, M Wang, T Chen, Y Wang, Z Gao… - Aging and …, 2022 - ncbi.nlm.nih.gov
The ketogenic diet (KD) is a low-carbohydrate, high-fat and adequate-protein diet. As a diet
mimicking fasting, it triggers the production of ketone bodies (KBs) and brings the body into …

[HTML][HTML] Impact of different types of diet on gut microbiota profiles and cancer prevention and treatment

RJ Klement, V Pazienza - Medicina, 2019 - mdpi.com
Diet is frequently considered as a food regimen focused on weight loss, while it is actually
the sum of food consumed by the organism. Western diets, modern lifestyle, sedentary …

[HTML][HTML] Do lower-carbohydrate diets increase total energy expenditure? An updated and reanalyzed meta-analysis of 29 controlled-feeding studies

DS Ludwig, SL Dickinson, B Henschel… - The Journal of …, 2021 - Elsevier
Background The effect of macronutrient composition on total energy expenditure (TEE)
remains controversial, with divergent findings among studies. One source of heterogeneity …

[HTML][HTML] Impact of a ketogenic diet intervention during radiotherapy on body composition: III—final results of the KETOCOMP study for breast cancer patients

RJ Klement, CE Champ, U Kämmerer… - Breast Cancer …, 2020 - Springer
Background Obesity and low muscle mass are associated with worse outcomes of breast
cancer patients. We conducted a controlled trial to study the impact of a ketogenic diet (KD) …

[HTML][HTML] Relationships between hyperinsulinaemia, magnesium, vitamin D, thrombosis and COVID-19: rationale for clinical management

ID Cooper, CAP Crofts, JJ DiNicolantonio… - Open …, 2020 - openheart.bmj.com
Risk factors for COVID-19 patients with poorer outcomes include pre-existing conditions:
obesity, type 2 diabetes mellitus, cardiovascular disease (CVD), heart failure, hypertension …