Background Previous studies have reported an extremely unbalanced global access to
opioid analgesics. We aimed to determine contemporary trends and patterns of opioid …

Background and Aim Chronic musculoskeletal pain is common and associated with more
general healthcare-seeking. However, musculoskeletal-related healthcare utilization is …

Background To examine time trends and characteristics of calls related to opioid poisonings
reported to the National Poison Centre and opioid sales in Switzerland. Methods We used …

Over the past decade opioid use has risen globally. The causes and consequences of this
increase, especially in Europe, are poorly understood. We conducted a population-based …

Background Medication use assessment has a critical role in promoting the effective and
rational use of pharmaceutical medications. There are no studies that have explored the …

Purpose Significant increases in opioid utilisation have been reported in many countries in
recent decades. This study investigated strong opioid prescribing in Irish General Medical …

Purpose We sought to compare trends in opioid purchasing between developed and
developing economies to understand patterns of opioid consumption, and how they were …

Background Opioid use has increased globally in the recent decade. Although pain remains
a significant problem among older adults, susceptibility to opioid-related harms highlights …

Abstract Background and Aims Persons with substance use disorders (SUDs) are at
elevated risk of suicide death. We identified novel risk factors and interactions that predict …

Background The risk of chronic opioid use after surgery for Crohn's disease (CD) is not
known. Aim The aim of this study is to examine the chronic opioid use after surgery …