PCR-based diagnostics for infectious diseases: uses, limitations, and future applications in acute-care settings
S Yang, RE Rothman - The Lancet infectious diseases, 2004 - thelancet.com
Molecular diagnostics are revolutionising the clinical practice of infectious disease. Their
effects will be significant in acute-care settings where timely and accurate diagnostic tools …
effects will be significant in acute-care settings where timely and accurate diagnostic tools …
Point-of-care diagnostics for global health
P Yager, GJ Domingo, J Gerdes - Annu. Rev. Biomed. Eng., 2008 - annualreviews.org
Biomedical engineers have traditionally developed technologies in response to the needs of
the developed world's medical community. As a result, the diagnostic systems on which they …
the developed world's medical community. As a result, the diagnostic systems on which they …
Macrolide resistance in Campylobacter jejuni and Campylobacter coli
A Gibreel, DE Taylor - Journal of Antimicrobial Chemotherapy, 2006 - academic.oup.com
Infection with Campylobacter jejuni is now considered to be the most common cause of
acute bacterial gastroenteritis in humans worldwide. It occurs more frequently than infections …
acute bacterial gastroenteritis in humans worldwide. It occurs more frequently than infections …
Exploiting molecular methods to explore endodontic infections: part 1—current molecular technologies for microbiological diagnosis
JF Siqueira Jr, IN Rôças - Journal of endodontics, 2005 - Elsevier
Endodontic infections have been traditionally studied by culture-dependent methods.
However, as with other areas of clinical microbiology, culture-based investigations are …
However, as with other areas of clinical microbiology, culture-based investigations are …
Mechanisms of antimicrobial resistance: their clinical relevance in the new millennium
AM Sefton - Drugs, 2002 - Springer
Antimicrobials show selective toxicity. Suitable targets for antimicrobials to act at include the
bacterial cell wall, bacterial protein and folic acid synthesis, nucleic acid metabolism in …
bacterial cell wall, bacterial protein and folic acid synthesis, nucleic acid metabolism in …
PCR methodology as a valuable tool for identification of endodontic pathogens
JF Siqueira Jr, IN Rôças - Journal of dentistry, 2003 - Elsevier
Objectives: This paper reviews the principles of polymerase chain reaction (PCR)
methodology, its application in identification of endodontic pathogens and the perspectives …
methodology, its application in identification of endodontic pathogens and the perspectives …
Molecular genetic methods for the diagnosis of fastidious microorganisms
F Fenollar, D Raoult - Apmis, 2004 - Wiley Online Library
Technological innovations in the detection and identification of microorganisms using
molecular techniques such as polymerase chain reaction (PCR) have ushered in a new era …
molecular techniques such as polymerase chain reaction (PCR) have ushered in a new era …
Microbiological evaluation of acute periradicular abscesses by DNA-DNA hybridization
JF Siqueira Jr, IN Rôças, R Souto, M de Uzeda… - Oral Surgery, Oral …, 2001 - Elsevier
Objective: The purpose of the present investigation was to examine the microbiota of acute
periradicular abscesses of endodontic origin by using a molecular genetic method. Study …
periradicular abscesses of endodontic origin by using a molecular genetic method. Study …
An integrated microfluidic platform for sensitive and rapid detection of biological toxins
RJ Meagher, AV Hatch, RF Renzi, AK Singh - Lab on a Chip, 2008 - pubs.rsc.org
Towards designing a portable diagnostic device for detecting biological toxins in bodily
fluids, we have developed microfluidic chip-based immunoassays that are rapid (< 20 …
fluids, we have developed microfluidic chip-based immunoassays that are rapid (< 20 …
A rapid DNA biosensor for the molecular diagnosis of infectious disease
Treating patients with infectious diseases relies heavily on rapid and proper diagnosis.
Molecular detection such as PCR has become increasingly important and efforts have been …
Molecular detection such as PCR has become increasingly important and efforts have been …