Introduction Photodynamic therapy (PDT) is a two-step treatment involving the
administration of a photosensitive agent followed by its activation at a specific light …

Photodynamic therapy (PDT) is a clinically approved, minimally invasive therapeutic
procedure that can exert a selective cytotoxic activity toward malignant cells. The procedure …

Glioblastoma is the most common form of adult brain cancer and remains one of the
deadliest of human cancers. The current standard-of-care involves maximal tumor resection …

Background Patients suffering from malignant gliomas have a poor prognosis. For the
surgical treatment of these tumors, 5‐aminolevulinic acid (5‐ALA) has become a new …

Photodynamic therapy (PDT) has received increased attention since the regulatory
approvals have been granted to several photosensitizing drugs and light applicators …

As unique molecules with both therapeutic and diagnostic properties, porphyrin derivatives
have been extensively employed for cancer treatment. Porphyrins not only show powerful …

A successful cure of cancer by biopharmaceuticals with intracellular targets is dependent on
both specific and sufficient delivery of the drug to the cytosol or nuclei of malignant cells …

As clinical nanomedicine has emerged over the past two decades, phototherapeutic
advancements using nanotechnology have also evolved and impacted disease …

Abstract Background and Objective Limited knowledge of the light and temperature
distribution within the target volume in combination with non‐selective accumulation of the …

Cancer is the leading cause of death worldwide and several anticancer therapies take
advantage of the ability of reactive oxygen species to kill cancer cells. Added to this is the …