Antisense-mediated modulation of pre-mRNA splicing is an attractive therapeutic strategy for
genetic diseases. Currently, there are few examples of modulation of pre-mRNA splicing …

Minimal artificial cells (MACs) are self-assembled chemical systems able to mimic the
behavior of living cells at a minimal level, ie to exhibit self-maintenance, self-reproduction …

Recent developments show that the standardization of cloud service descriptions and
exchange leads the way for the rise of cloud federations. In these federations CSPs (cloud …

Background Over the last two decades, lipid compartments (liposomes, lipid-coated
droplets) have been extensively used as in vitro" minimal" cell models. In particular, simple …

Abstract The 2′‐O, 4′‐C‐methylene‐bridged or locked nucleic acid (2′, 4′‐BNA/LNA),
with an N‐type sugar conformation, effectively improves duplex‐forming ability. 2′, 4 …

There has been a growing interest in developing chemically modified nucleotides for
diagnostics or therapeutics. Among the list of the artificial nucleotides, bridged nucleic acids …

Artificial nucleic acids are widely used in various technologies, such as nucleic acid
therapeutics and DNA nanotechnologies requiring excellent duplex‐forming abilities and …

Locked nucleic acids (LNA), conformationally restricted nucleotide analogues, are known to
enhance pairing stability and selectivity toward complementary strands. With the aim to …

Metal‐mediated base pairs have widespread applications, such as in DNA‐metal
nanodevices and sensors. Here, we focused on their sugar conformation in duplexes and …

The hybridisation and melting of DNA strands are critical steps in many biological
processes, but still a deeper understanding of the kinetics is lacking. This is evident from the …