RNA-binding proteins play key roles in regulation of gene expression via recognition of
structural features in RNA molecules. Here we apply a quantitative RNA pull-down approach …

Pre-mRNA splicing is critical for cells, as defects in this process can lead to altered open
reading frames and defective proteins, potentially causing neurodegenerative diseases and …

RNA-binding proteins (RBPs) establish posttranscriptional gene regulation (PTGR) by
coordinating the maturation, editing, transport, stability, and translation of cellular RNAs. A …

The conserved SR-like protein Npl3 promotes splicing of diverse pre-mRNAs. However, the
RNA sequence (s) recognized by the RNA Recognition Motifs (RRM1 & RRM2) of Npl3 …

Most eukaryotic mRNAs accommodate alternative sites of poly (A) addition in the
3'untranslated region in order to regulate mRNA function. Here, we present a systematic …

The yeast protein Ipa1 was recently discovered to interact with the Ysh1 endonuclease of
the pre-mRNA cleavage and polyadenylation (C/P) machinery, and Ipa1 mutation impairs …

RNA biology has recently seen an explosion of data due to advances in RNA sequencing,
proteomic, and RNA imaging technologies. In this review, we highlight progress that has …

Abstract Translation Complex Profile Sequencing (TCP-seq), a protocol that was developed
and implemented on Saccharomyces cerevisiae, provides the footprints of the small subunit …

Cytoplasmic poly (A) binding protein (PABP) is an essential translation factor that binds to
the 3'tail of mRNAs to promote translation and regulate mRNA stability. PABPC1 is the most …

Efficient gene expression requires properly matured mRNAs for functional transcript
translation. Several factors including the guard proteins monitor maturation and act as …