[HTML][HTML] The lost and found: unraveling the functions of orphan genes

AZ Fakhar, J Liu, KM Pajerowska-Mukhtar… - Journal of …, 2023 - mdpi.com
Orphan Genes (OGs) are a mysterious class of genes that have recently gained significant
attention. Despite lacking a clear evolutionary history, they are found in nearly all living …

Advanced network pharmacology study reveals multi-pathway and multi-gene regulatory molecular mechanism of Bacopa monnieri in liver cancer based on data …

M Sadaqat, M Qasim, MT ul Qamar, MS Masoud… - Computers in biology …, 2023 - Elsevier
Liver cancer is a malignant tumor that grows on the surface or inside the liver. The leading
cause is a viral infection with hepatitis B or C virus. Natural products and their structural …

Discovery of potential phytochemicals as inhibitors of TcdB, a major virulence factors of Clostridioides difficile

MA Alamri, MH Tariq, M Tahir ul Qamar… - Journal of …, 2023 - Taylor & Francis
Clostridioides difficile is a gram-positive bacterium which is associated with different
gastrointestinal related infections, and the numbers of cases related to it are continuously …

[PDF][PDF] Face mask detection model based on deep CNN technique using AWS

R Tandon, A Sayed, MA Hashmi - International Journal of …, 2023 - researchgate.net
Since the outbreak of the epidemic coronavirus infection (COVID-19) in Wuhan, it's become
a public health concern in China, and subsequently globally. That pandemic consumes …

Unveiling MurE ligase potential inhibitors for treating multi-drug resistant Acinetobacter baumannii

A Altharawi, SM Alqahatani, MM Alanazi… - Journal of …, 2024 - Taylor & Francis
Acinetobacter baumannii is an opportunistic pathogen with ability to cause serious infection
such as bacteremia, ventilator associated pneumonia, and wound infections. As strains of A …

[HTML][HTML] Identification of novel inhibitors against hantaviruses through 2D fingerprinting and molecular modeling approaches

A Alshammari - Frontiers in Immunology, 2023 - frontiersin.org
With the immensely growing outbreaks of hantavirus with still no effective treatment
available, there is an urgent need of exploring new computational approaches which will …

[HTML][HTML] Targeting Toxoplasma gondii ME49 TgAPN2: A Bioinformatics Approach for Antiparasitic Drug Discovery

A Altharawi - Molecules, 2023 - mdpi.com
As fewer therapeutic options are available for treating toxoplasmosis, newer antiparasitic
drugs that can block TgAPN2 M1 aminopeptidase are of significant value. Herein, we …

Selected phytochemicals of Momordica charantia L. as potential anti-DENV-2 through the docking, DFT and molecular dynamic simulation

AKMM Huq, M Roney, AR Issahaku… - Journal of …, 2023 - Taylor & Francis
Dengue fever is now one of the major global health concerns particularly for tropical and sub-
tropical countries. However, there has been no FDA approved medication to treat dengue …

Discovery of a Novel Public Antibody Lineage Correlated with Inactivated SARS-CoV-2 Vaccine and the Resultant Neutralization Activity

J Wang, S Ni, Q Chen, C Wang, H Liu, L Huang… - papers.ssrn.com
While the SARS-CoV-2 vaccine offers 70-95% protection effectiveness against Coronavirus
disease 2019 (COVID-19), a portion of recipients do not produce adequate protective …