Krüppel-like factor 4 (KLF4) is an evolutionarily conserved zinc finger-containing
transcription factor that regulates diverse cellular processes such as cell growth …

BMP signaling plays an important role in dentin development. BMPs and antagonists
regulate odontoblast differentiation and downstream gene expression via canonical Smad …

Osteogenic differentiation of human bone marrow‐derived mesenchymal stem cells
(hBMSCs) is essential for the human bone formation, and emerging evidence shows that …

Background. Despite recent advances in scientific knowledge and clinical practice,
management, and treatment of breast cancer, as one of the leading causes of female …

Background MicroRNA-21 (miR-21) is overexpressed in most inflammatory diseases, but its
physiological role in gut inflammation and tissue injury is poorly understood. The goal of this …

The early macrophage response to biomaterials has been shown to be a critical and
predictive determinant of downstream outcomes. When properly prepared, bioscaffolds …

Bone remodeling is balanced by bone formation and bone resorption as well as by
alterations in the quantities and functions of seed cells, leading to either the maintenance or …

Osteogenic differentiation of human bone marrow-derived mesenchymal stem cells
(hBMSCs) is quite important for the bone formation. Bone morphogenetic proteins (BMPs) …

Non-coding RNAs (ncRNAs) have evolved in eukaryotes as epigenetic regulators of gene
expression. The most abundant regulatory ncRNAs are the 20–24 nt small microRNAs …

Aim To compare the mineralization inductive capacity of Biodentine and Bioaggregate with
Mineral trioxide aggregate (MTA) and to investigate possible signaling pathways of …