MicroRNAs and bone regeneration

T Nakasa, M Yoshizuka, M Andry Usman… - Current …, 2015 - ingentaconnect.com
Bone has multiple functions, both morphologically and physiologically, and it frequently
features in the pathological condition, including fracture and osteoporosis. For bone …

BMP-2 induced Dspp transcription is mediated by Dlx3/Osx signaling pathway in odontoblasts

G Yang, G Yuan, M MacDougall, C Zhi, S Chen - Scientific reports, 2017 - nature.com
Dentin sialophosphoprotein (Dspp) as a differentiation marker of odontoblasts is regulated
by BMP-2. However, the intimate mechanism is still unknown. Transcription factors Dlx3 and …

A species-specific miRNA participates in biomineralization by targeting CDS regions of Prisilkin-39 and ACCBP in Pinctada fucata

X Zhu, Y Chen, Z Zhang, S Zhao, L Xie, R Zhang - Scientific Reports, 2020 - nature.com
Biomineralization is a sophisticated biological process precisely regulated by multiple
molecules and pathways. Accumulating miRNAs have been identified in invertebrates but …

SP1 regulates KLF4 via SP1 binding motif governed by DNA methylation during odontoblastic differentiation of human dental pulp cells

Z Sun, S Yu, S Chen, H Liu… - Journal of Cellular …, 2019 - Wiley Online Library
Objective DNA methylation is a critical epigenetic modulation in regulating gene expression
in cell differentiation process, however, its detailed molecular mechanism during …

Bicarbonate transport during enamel maturation

K Yin, ML Paine - Calcified tissue international, 2017 - Springer
Amelogenesis (tooth enamel formation) is a biomineralization process consisting primarily of
two stages (secretory stage and maturation stage) with unique features. During the secretory …

Identification and profile of microRNAs in Xiang pig testes in four different ages detected by Solexa sequencing

ZY Luo, XL Dai, XQ Ran, YX Cen, X Niu, S Li… - Theriogenology, 2018 - Elsevier
To further understand the role of microRNA (miRNA) during testicular development, we
constructed four small RNA libraries from the testes of the Chinese indigenous Xiang pig at …

Downregulation of microRNA‐143‐5p is required for the promotion of odontoblasts differentiation of human dental pulp stem cells through the activation of the mitogen …

BL Wang, Z Wang, X Nan, QC Zhang… - Journal of cellular …, 2019 - Wiley Online Library
MicroRNAs (miRNAs) play critical roles in various biological processes including cell
differentiation. Some researchers suggested that the p38 mitogen‐activated protein kinases …

Transcriptional factor ATF6 is involved in odontoblastic differentiation

JW Kim, H Choi, BC Jeong, SH Oh… - Journal of Dental …, 2014 - journals.sagepub.com
ATF6 is an endoplasmic reticulum (ER) membrane-bound transcription factor that regulates
various cellular functions. The purpose of this study was to investigate the role of ATF6 in …

A Peptide Nucleic Acid (PNA) Masking the miR-145-5p Binding Site of the 3′UTR of the Cystic Fibrosis Transmembrane Conductance Regulator (CFTR) mRNA …

S Sultan, A Rozzi, J Gasparello, A Manicardi… - Molecules, 2020 - mdpi.com
Peptide nucleic acids (PNAs) have been demonstrated to be very useful tools for gene
regulation at different levels and with different mechanisms of action. In the last few years the …

miR-675 promotes odontogenic differentiation of human dental pulp cells by epigenetic regulation of DLX3

L Zeng, N Zhao, F Li, D Han, Y Liu, H Liu, S Sun… - Experimental cell …, 2018 - Elsevier
In a previous study, we showed that microRNA-675 (miR-675) was significantly down-
regulated in patients with tricho-dento-osseous (TDO) syndrome. One of the main features of …