Enamel mineralization is accompanied by the release of protons into the extracellular matrix,
which is buffered to regulate the pH value in the local microenvironment. The present study …

Abstract Purpose of Review The ebb and flow of genetic influence relative to the
understanding of craniofacial and dental disorders has evolved into a tacit acceptance of the …

As a kind of endogenous noncoding small RNA, MicroRNA (miRNA) plays important roles of
regulation to various physiological functions, while its affections on senescence of human …

Dentinogenesis imperfecta and dentin dysplasia are two common types of genetic oral
diseases resulted from the aberrant differentiation of odontoblast. Understanding the …

Nanog is a well‐known transcription factor that plays a fundamental role in stem cell self‐
renewal and the maintenance of their pluripotent cell identity. There remains a large data …

Pulmonary hypertension (PH) is characterized by vascular remodeling predominantly driven
by a phenotypic switching in pulmonary artery smooth muscle cells (PASMCs). However, the …

Background: Neonatal pneumonia is a common disease in the neonatal period with a high
incidence and death. This study aimed to investigate the molecular mechanism and effect of …

Epigenetics refers to the mechanisms such as DNA methylation and histone modification
that influence gene expression without altering the DNA sequence. These epigenetic …

Cellular differentiation is caused by highly controlled modifications in the gene expression
but rarely involves a change in the DNA sequence itself. Histone acetylation is a major …

MicroRNAs (miRNAs) are a class of naturally occurring small non-coding RNAs that post-
transcriptionally regulate gene expression in organisms. Most mammalian miRNAs …