Amorphous solid dispersion (ASD) is one of the most effective approaches for delivering
poorly soluble drugs. In ASDs, polymeric materials serve as the carriers in which the drugs …

Introduction Most new drug candidates under development are poorly water-soluble, which
are related to multiple pharmaceutical issues, increasing the bioavailability of these drugs by …

In this study, shell-core fibers were successfully prepared by using Eudragit S100 (ES100)
and poly (vinyl alcohol)(PVA)/pectin (PEC) through coaxial electrospinning technology. The …

The purpose of this study was to investigate the efficacy of hydrophilic polymers in a solid
dispersion formulation in improving the solubility and dissolution rate of rivaroxaban (RXB) …

This study aimed to develop microspheres using water-soluble carriers and surfactants to
improve the solubility, dissolution, and oral bioavailability of rivaroxaban (RXB). RXB-loaded …

Curcumin (CUR) has gained increasing interest worldwide due to multiple biological
activities. However, the therapeutic application remains limited because of its low aqueous …

Poor aqueous solubility of terpenophenolic compound Cannabidiol (CBD) is a major issue
in the widespread use of this promising therapeutic polyphenol. Moreover, choosing the …

Amorphous solid dispersions enhance solubility and oral bioavailability of poorly water-
soluble drugs. The escalating number of drugs with poor aqueous solubility, poor …

Chemical modification of chitosan derivatives with hydrophobic fatty acids to enhance their
self-aggregation behavior is well established. Previously our group reported low molecular …

Objectives Rivaroxaban (RXB), a novel Xa inhibitor having groundbreaking therapeutic
potential. However, this drug is associated with few limitations, including its …