Simulated physiological oocyte maturation has side effects on bovine oocytes and embryos

EM Razza, HS Pedersen, L Stroebech… - Journal of Assisted …, 2019 - Springer
Purpose Oocyte maturation is a complex process involving nuclear and cytoplasmic
modulations, during which oocytes acquire their ability to become fertilized and support …

[HTML][HTML] Pre-IVM treatment with C-type natriuretic peptide in the presence of cysteamine enhances bovine oocytes antioxidant defense ability and developmental …

J Zhenwei, Z Xianhua - Iranian journal of veterinary research, 2019 - ncbi.nlm.nih.gov
Background: The use of C-type natriuretic peptide (CNP) combined with cysteamine during
pre-in vitro maturation (IVM) can help establish an effective pre-IVM system. Aims: This study …

[HTML][HTML] cAMP modulators before in vitro maturation decrease DNA damage and boost developmental potential of sheep oocytes

DA Medina-Chávez, I Sánchez-Ajofrín, P Peris-Frau… - Animals, 2021 - mdpi.com
Simple Summary Oocyte in vitro maturation has massive potential for the generation of great
numbers of embryos for research and for the application of assisted reproductive …

Molecular characteristics of oocytes and somatic cells of follicles at different sizes that influence in vitro oocyte maturation and embryo production

FTG Bezerra, AMP Dau, R Van Den Hurk… - Domestic Animal …, 2021 - Elsevier
During the last 10 to 15 yr, in vitro research to predict antral follicle growth and oocyte
maturation has delivered interesting advances in the knowledge of processes regulating …

[HTML][HTML] Transferrin and antioxidants partly prevented mouse oocyte oxidative damage induced by exposure of cumulus-oocyte complexes to endometrioma fluid

Z Ren, J Huang, C Zhou, L Jia, M Li, X Liang… - Journal of Ovarian …, 2020 - Springer
Background Exposure of oocytes to the endometrioma fluid has an adverse effect on
embryonic quality. To determine whether adding transferrin and antioxidants to culture …

[HTML][HTML] Mitochondrial function in immature bovine oocytes is improved by an increase of cellular cyclic AMP

S Hashimoto, M Yamanaka, T Yamochi, H Iwata… - Scientific Reports, 2019 - nature.com
Although in vitro maturation (IVM) of oocytes is important for assisted reproduction, the rate
of development of embryos from IVM oocytes is lower than from their in vivo counterparts. It …

[HTML][HTML] Impact of preovulatory follicle maturity on oocyte metabolism and embryo development

HM Clark, AE Stokes, JL Edwards, RR Payton… - PNAS …, 2024 - academic.oup.com
Improved oocyte competence for embryo development and pregnancy was observed
following ovulation of preovulatory follicles with greater physiological maturity, as indicated …

Building a better mouse embryo assay: effects of mouse strain and in vitro maturation on sensitivity to contaminants of the culture environment

JR Herrick, T Paik, KJ Strauss, WB Schoolcraft… - Journal of assisted …, 2016 - Springer
Purpose The aim of this study is to compare the sensitivity of the standard one-cell mouse
embryo assay (MEA) to that using in vitro-matured oocytes from hybrid and outbred mice …

Mice born to females with oocyte-specific deletion of mitofusin 2 have increased weight gain and impaired glucose homeostasis

BM Garcia, TS Machado, KF Carvalho… - Molecular Human …, 2020 - academic.oup.com
Offspring born to obese and diabetic mothers are prone to metabolic diseases, a phenotype
that has been linked to mitochondrial dysfunction and endoplasmic reticulum (ER) stress in …

The SPOM-adapted IVM system improves in vitro production of bovine embryos

GR Leal, MAG Graciosa, CAS Monteiro, R Pasolini… - Theriogenology, 2020 - Elsevier
This study aimed to test the effects of an IVM SPOM adaptation (SPOM-adapted IVM) on the
production, total number of cells (TNC), apoptosis, and cryotolerance (post-warming survival …