Regenerative stem cell therapy for neurodegenerative diseases: an overview

F Sivandzade, L Cucullo - International journal of molecular sciences, 2021 - mdpi.com
Neurodegenerative diseases resulting from the progressive loss of structure and/or function
of neurons contribute to different paralysis degrees and loss of cognition and sensation. The …

Functional role of mesenchymal stem cells in the treatment of chronic neurodegenerative diseases

D Lo Furno, G Mannino… - Journal of cellular …, 2018 - Wiley Online Library
Mesenchymal stem cells (MSCs) can differentiate into not only cells of mesodermal
lineages, but also into endodermal and ectodermal derived elements, including neurons …

A review of stem cell therapy: an emerging treatment for dementia in alzheimer's and Parkinson's disease

AU Pradhan, O Uwishema, H Onyeaka… - Brain and …, 2022 - Wiley Online Library
Aim This article aims to study the benefits and disadvantages of stem cell therapy, especially
for patients who have dementia. Methods The databases PubMed, Google Scholar, and the …

Accelerating stem cell trials for Alzheimer's disease

JG Hunsberger, M Rao, J Kurtzberg, JWM Bulte… - The Lancet …, 2016 - thelancet.com
At present, no effective cure or prophylaxis exists for Alzheimer's disease. Symptomatic
treatments are modestly effective and offer only temporary benefit. Advances in induced …

Stem cell therapy in Alzheimer's disease: possible benefits and limiting drawbacks

M Alipour, SM Nabavi, L Arab, M Vosough… - Molecular biology …, 2019 - Springer
Alzheimer's disease (AD) is the sixth leading cause of death globally and the main reason
for dementia in elderly people. AD is a long-term and progressive neurodegenerative …

Mesenchymal stem cell therapy and Alzheimer's disease: current status and future perspectives

J Kim, Y Lee, S Lee, K Kim, M Song… - Journal of Alzheimer's …, 2020 - content.iospress.com
Alzheimer's disease (AD) is the most common progressive neurodegenerative disease
worldwide, but its cause remains unclear. Although a few drugs can provide temporary and …

Transplantation of bone marrow mesenchymal stem cells improves cognitive deficits and alleviates neuropathology in animal models of Alzheimer's disease: a meta …

C Qin, Y Lu, K Wang, L Bai, G Shi, Y Huang… - Translational …, 2020 - Springer
Background Alzheimer's disease is a neurodegenerative disorder. Therapeutically, a
transplantation of bone marrow mesenchymal stem cells (BMMSCs) can play a beneficial …

Survivin in autoimmune diseases

G Gravina, C Wasén, MJ Garcia-Bonete, M Turkkila… - Autoimmunity …, 2017 - Elsevier
Survivin is a protein functionally important for cell division, apoptosis, and possibly, for micro-
RNA biogenesis. It is an established marker of malignant cell transformation. In non …

Administrations of human adult ischemia-tolerant mesenchymal stem cells and factors reduce amyloid beta pathology in a mouse model of Alzheimer's disease

T Harach, F Jammes, C Muller, N Duthilleul… - Neurobiology of …, 2017 - Elsevier
The impact of human adult ischemia-tolerant mesenchymal stem cells (hMSCs) and factors
(stem cell factors) on cerebral amyloid beta (Aβ) pathology was investigated in a mouse …

Prospects for the application of mesenchymal stem cells in Alzheimer's disease treatment

F Chakari-Khiavi, S Dolati, A Chakari-Khiavi… - Life sciences, 2019 - Elsevier
Alzheimer's disease (AD) as a dementia and neurodegenerative disease, is mostly
prevalent among people more than 65 years. AD is mostly manifested in the form of …