[HTML][HTML] Cognitive impairment in schizophrenia: aetiology, pathophysiology, and treatment

RA McCutcheon, RSE Keefe, PK McGuire - Molecular psychiatry, 2023 - nature.com
Cognitive deficits are a core feature of schizophrenia, account for much of the impaired
functioning associated with the disorder and are not responsive to existing treatments. In this …

Illuminating dendritic function with computational models

P Poirazi, A Papoutsi - Nature Reviews Neuroscience, 2020 - nature.com
Dendrites have always fascinated researchers: from the artistic drawings by Ramon y Cajal
to the beautiful recordings of today, neuroscientists have been striving to unravel the …

[HTML][HTML] Flexible reuse of cortico-hippocampal representations during encoding and recall of naturalistic events

ZM Reagh, C Ranganath - Nature Communications, 2023 - nature.com
Although every life event is unique, there are considerable commonalities across events.
However, little is known about whether or how the brain flexibly represents information about …

[HTML][HTML] Neocortical synaptic engrams for remote contextual memories

JH Lee, WB Kim, EH Park, JH Cho - Nature Neuroscience, 2023 - nature.com
While initial encoding of contextual memories involves the strengthening of hippocampal
circuits, these memories progressively mature to stabilized forms in neocortex and become …

[HTML][HTML] Prediction and memory: A predictive coding account

HC Barron, R Auksztulewicz, K Friston - Progress in neurobiology, 2020 - Elsevier
The hippocampus is crucial for episodic memory, but it is also involved in online prediction.
Evidence suggests that a unitary hippocampal code underlies both episodic memory and …

[HTML][HTML] Toward an integration of deep learning and neuroscience

AH Marblestone, G Wayne, KP Kording - Frontiers in computational …, 2016 - frontiersin.org
Neuroscience has focused on the detailed implementation of computation, studying neural
codes, dynamics and circuits. In machine learning, however, artificial neural networks tend …

[PDF][PDF] How can hearing loss cause dementia?

TD Griffiths, M Lad, S Kumar, E Holmes, B McMurray… - Neuron, 2020 - cell.com
Epidemiological studies identify midlife hearing loss as an independent risk factor for
dementia, estimated to account for 9% of cases. We evaluate candidate brain bases for this …

An integrative view of human hippocampal function: Differences with other species and capacity considerations

R Quian Quiroga - Hippocampus, 2023 - Wiley Online Library
We describe an integrative model that encodes associations between related concepts in
the human hippocampal formation, constituting the skeleton of episodic memories. The …

Domain generality versus modality specificity: The paradox of statistical learning

R Frost, BC Armstrong, N Siegelman… - Trends in cognitive …, 2015 - cell.com
Statistical learning (SL) is typically considered to be a domain-general mechanism by which
cognitive systems discover the underlying distributional properties of the input. However …

Hippocampal spatial view cells for memory and navigation, and their underlying connectivity in humans

ET Rolls - Hippocampus, 2023 - Wiley Online Library
Hippocampal and parahippocampal gyrus spatial view neurons in primates respond to the
spatial location being looked at. The representation is allocentric, in that the responses are …