ICAM-1: A master regulator of cellular responses in inflammation, injury resolution, and tumorigenesis
ICAM-1 is a cell surface glycoprotein and an adhesion receptor that is best known for
regulating leukocyte recruitment from circulation to sites of inflammation. However, in …
regulating leukocyte recruitment from circulation to sites of inflammation. However, in …
The healing power of neutrophils
M Phillipson, P Kubes - Trends in immunology, 2019 - cell.com
Neutrophils promptly accumulate in large numbers at sites of tissue injury. Injuries to the skin
or mucosae disrupt barriers against the external environment, and the bactericidal actions of …
or mucosae disrupt barriers against the external environment, and the bactericidal actions of …
Pectin in diet: Interactions with the human microbiome, role in gut homeostasis, and nutrient-drug interactions
MS Elshahed, A Miron, AC Aprotosoaie… - Carbohydrate Polymers, 2021 - Elsevier
Pectins are a part of daily diet as well as food additives that are indigestible polysaccharides
by human enzymes, however, they can be easily degraded by gut bacteria with the …
by human enzymes, however, they can be easily degraded by gut bacteria with the …
[HTML][HTML] NADPH oxidases and ROS signaling in the gastrointestinal tract
Reactive oxygen species (ROS), initially categorized as toxic by-products of aerobic
metabolism, have often been called a double-edged sword. ROS are considered …
metabolism, have often been called a double-edged sword. ROS are considered …
The neutrophil: constant defender and first responder
N Fine, N Tasevski, CA McCulloch… - Frontiers in …, 2020 - frontiersin.org
The role of polymorphonuclear neutrophils (PMNs) in biology is often recognized during
pathogenesis associated with PMN hyper-or hypo-functionality in various disease states …
pathogenesis associated with PMN hyper-or hypo-functionality in various disease states …
CD177+ neutrophils as functionally activated neutrophils negatively regulate IBD
G Zhou, L Yu, L Fang, W Yang, T Yu, Y Miao, M Chen… - Gut, 2018 - gut.bmj.com
Background Neutrophils are accumulated in inflamed mucosa of IBD and play an important
role in the pathogenesis. CD177 is expressed in neutrophils specifically and upregulated …
role in the pathogenesis. CD177 is expressed in neutrophils specifically and upregulated …
Unveiling the gut-brain axis: structural and functional analogies between the gut and the choroid plexus vascular and immune barriers
S Carloni, M Rescigno - Seminars in Immunopathology, 2022 - Springer
The vasculature plays an essential role in the development and maintenance of blood-tissue
interface homeostasis. Knowledge on the morphological and functional nature of the blood …
interface homeostasis. Knowledge on the morphological and functional nature of the blood …
[HTML][HTML] Intercellular adhesion molecule 1 functions as an efferocytosis receptor in inflammatory macrophages
HL Wiesolek, TM Bui, JJ Lee, P Dalal… - The American journal of …, 2020 - Elsevier
Intercellular adhesion molecule-1 (ICAM-1) is up-regulated during inflammation by several
cell types. ICAM-1 is best known for its role in mediating leukocyte adhesion to endothelial …
cell types. ICAM-1 is best known for its role in mediating leukocyte adhesion to endothelial …
GPR101 mediates the pro-resolving actions of RvD5n-3 DPA in arthritis and infections
N-3 docosapentaenoic acid–derived resolvin D5 (RvD5n-3 DPA) is diurnally regulated in
peripheral blood and exerts tissue-protective actions during inflammatory arthritis. Here …
peripheral blood and exerts tissue-protective actions during inflammatory arthritis. Here …
Intercellular adhesion molecule 1: more than a leukocyte adhesion molecule
CD Haydinger, LM Ashander, ACR Tan, JR Smith - Biology, 2023 - mdpi.com
Simple Summary Intercellular adhesion molecule 1 (ICAM-1) is a protein produced by cells
in blood vessel walls, as well as many other cell types. It localizes to the surface of these …
in blood vessel walls, as well as many other cell types. It localizes to the surface of these …