The Genetics of Axon Guidance and Axon Regeneration in Caenorhabditis elegans

AD Chisholm, H Hutter, Y Jin, WG Wadsworth - Genetics, 2016 - academic.oup.com
The correct wiring of neuronal circuits depends on outgrowth and guidance of neuronal
processes during development. In the past two decades, great progress has been made in …

Neuronal guidance genes in health and diseases

J Yuasa-Kawada, M Kinoshita-Kawada, Y Tsuboi… - Protein & …, 2023 - academic.oup.com
Neurons migrate from their birthplaces to the destinations, and extending axons navigate to
their synaptic targets by sensing various extracellular cues in spatiotemporally controlled …

RNA docking and local translation regulate site-specific axon remodeling in vivo

HHW Wong, JQ Lin, F Ströhl, CG Roque, JM Cioni… - Neuron, 2017 - cell.com
Nascent proteins can be positioned rapidly at precise subcellular locations by local protein
synthesis (LPS) to facilitate localized growth responses. Axon arbor architecture, a major …

[HTML][HTML] Satb1 regulates contactin 5 to pattern dendrites of a mammalian retinal ganglion cell

YR Peng, NM Tran, A Krishnaswamy, D Kostadinov… - Neuron, 2017 - cell.com
The size and shape of dendritic arbors are prime determinants of neuronal connectivity and
function. We asked how ON-OFF direction-selective ganglion cells (ooDSGCs) in mouse …

Ionotropic receptors specify the morphogenesis of phasic sensors controlling rapid thermal preference in Drosophila

G Budelli, L Ni, C Berciu, L van Giesen, ZA Knecht… - Neuron, 2019 - cell.com
Thermosensation is critical for avoiding thermal extremes and regulating body temperature.
While thermosensors activated by noxious temperatures respond to hot or cold, many …

Whole-exome sequencing and neurite outgrowth analysis in autism spectrum disorder

R Hashimoto, T Nakazawa, Y Tsurusaki… - Journal of human …, 2016 - nature.com
Autism spectrum disorder (ASD) is a complex group of clinically heterogeneous
neurodevelopmental disorders with unclear etiology and pathogenesis. Genetic studies …

The m6A reader YTHDF2 is a negative regulator for dendrite development and maintenance of retinal ganglion cells

F Niu, P Han, J Zhang, Y She, L Yang, J Yu, M Zhuang… - Elife, 2022 - elifesciences.org
The precise control of growth and maintenance of the retinal ganglion cell (RGC) dendrite
arborization is critical for normal visual functions in mammals. However, the underlying …

Deterministic and stochastic rules of branching govern dendrite morphogenesis of sensory neurons

A Palavalli, N Tizón-Escamilla, JF Rupprecht, T Lecuit - Current Biology, 2021 - cell.com
Dendrite morphology is necessary for the correct integration of inputs that neurons receive.
The branching mechanisms allowing neurons to acquire their type-specific morphology …

KDM5A mutations identified in autism spectrum disorder using forward genetics

L El Hayek, IO Tuncay, N Nijem, J Russell, S Ludwig… - Elife, 2020 - elifesciences.org
Autism spectrum disorder (ASD) is a constellation of neurodevelopmental disorders with
high phenotypic and genetic heterogeneity, complicating the discovery of causative genes …

[HTML][HTML] Branching mechanisms shaping dendrite architecture

V Lanoue, HM Cooper - Developmental biology, 2019 - Elsevier
A neuron's contribution to the information flow within a neural circuit is governed by the
structure of its dendritic arbor. The geometry of the dendritic arbor directly determines …