The Genetics of Axon Guidance and Axon Regeneration in Caenorhabditis elegans
The correct wiring of neuronal circuits depends on outgrowth and guidance of neuronal
processes during development. In the past two decades, great progress has been made in …
processes during development. In the past two decades, great progress has been made in …
Neuronal guidance genes in health and diseases
J Yuasa-Kawada, M Kinoshita-Kawada, Y Tsuboi… - Protein & …, 2023 - academic.oup.com
Neurons migrate from their birthplaces to the destinations, and extending axons navigate to
their synaptic targets by sensing various extracellular cues in spatiotemporally controlled …
their synaptic targets by sensing various extracellular cues in spatiotemporally controlled …
RNA docking and local translation regulate site-specific axon remodeling in vivo
Nascent proteins can be positioned rapidly at precise subcellular locations by local protein
synthesis (LPS) to facilitate localized growth responses. Axon arbor architecture, a major …
synthesis (LPS) to facilitate localized growth responses. Axon arbor architecture, a major …
[HTML][HTML] Satb1 regulates contactin 5 to pattern dendrites of a mammalian retinal ganglion cell
The size and shape of dendritic arbors are prime determinants of neuronal connectivity and
function. We asked how ON-OFF direction-selective ganglion cells (ooDSGCs) in mouse …
function. We asked how ON-OFF direction-selective ganglion cells (ooDSGCs) in mouse …
Ionotropic receptors specify the morphogenesis of phasic sensors controlling rapid thermal preference in Drosophila
G Budelli, L Ni, C Berciu, L van Giesen, ZA Knecht… - Neuron, 2019 - cell.com
Thermosensation is critical for avoiding thermal extremes and regulating body temperature.
While thermosensors activated by noxious temperatures respond to hot or cold, many …
While thermosensors activated by noxious temperatures respond to hot or cold, many …
Whole-exome sequencing and neurite outgrowth analysis in autism spectrum disorder
R Hashimoto, T Nakazawa, Y Tsurusaki… - Journal of human …, 2016 - nature.com
Autism spectrum disorder (ASD) is a complex group of clinically heterogeneous
neurodevelopmental disorders with unclear etiology and pathogenesis. Genetic studies …
neurodevelopmental disorders with unclear etiology and pathogenesis. Genetic studies …
The m6A reader YTHDF2 is a negative regulator for dendrite development and maintenance of retinal ganglion cells
F Niu, P Han, J Zhang, Y She, L Yang, J Yu, M Zhuang… - Elife, 2022 - elifesciences.org
The precise control of growth and maintenance of the retinal ganglion cell (RGC) dendrite
arborization is critical for normal visual functions in mammals. However, the underlying …
arborization is critical for normal visual functions in mammals. However, the underlying …
Deterministic and stochastic rules of branching govern dendrite morphogenesis of sensory neurons
Dendrite morphology is necessary for the correct integration of inputs that neurons receive.
The branching mechanisms allowing neurons to acquire their type-specific morphology …
The branching mechanisms allowing neurons to acquire their type-specific morphology …
KDM5A mutations identified in autism spectrum disorder using forward genetics
L El Hayek, IO Tuncay, N Nijem, J Russell, S Ludwig… - Elife, 2020 - elifesciences.org
Autism spectrum disorder (ASD) is a constellation of neurodevelopmental disorders with
high phenotypic and genetic heterogeneity, complicating the discovery of causative genes …
high phenotypic and genetic heterogeneity, complicating the discovery of causative genes …
[HTML][HTML] Branching mechanisms shaping dendrite architecture
V Lanoue, HM Cooper - Developmental biology, 2019 - Elsevier
A neuron's contribution to the information flow within a neural circuit is governed by the
structure of its dendritic arbor. The geometry of the dendritic arbor directly determines …
structure of its dendritic arbor. The geometry of the dendritic arbor directly determines …