[HTML][HTML] Oxymatrine Improves Oxidative Stress-Induced Senescence in HT22 Cells and Mice via the Activation of AMP-Activated Protein Kinase

N Maharajan, CM Lee, KA Vijayakumar, GW Cho - Antioxidants, 2023 - mdpi.com
The accumulation of oxidative stress is one of the important factors causing cellular
senescence. Oxymatrine (OM) is a natural quinolizidine alkaloid compound known for its …

An update in toxicology of ageing

L Rackova, M Mach, Z Brnoliakova - Environmental Toxicology and …, 2021 - Elsevier
The field of ageing research has been rapidly advancing in recent decades and it had
provided insight into the complexity of ageing phenomenon. However, as the organism …

[HTML][HTML] Senescent hepatocytes enhance natural killer cell activity via the CXCL‑10/CXCR3 axis

J Zang, J Ye, C Zhang, M Sha… - Experimental and …, 2019 - spandidos-publications.com
Cellular senescence and natural killer (NK) cells play an important role in liver diseases.
Chemokines, a component of the senescence‑associated secretory phenotype, can recruit …

Study on the mechanism of radix astragali against renal aging based on network pharmacology

Z Zhang, J Fang, D Sun, Y Zheng, X Liu… - Evidence‐Based …, 2022 - Wiley Online Library
Radix Astragali is widely used in the traditional Chinese medicine with the effect of
antiaging. The purpose of this study is to explore the main active ingredients and targets of …

Organismal aging and oxidants beyond macromolecules damage

MV Clement, L Luo - Proteomics, 2020 - Wiley Online Library
The relationship between oxidants and organismal aging was first articulated through the
free radical theory of aging. One of the major predictions of the free radical theory of aging is …

Effects of ultra-high dilutions of sodium butyrate on viability and gene expression in HEK 293 cells

S Olsen - Homeopathy, 2017 - thieme-connect.com
Background: Several recent studies reported the capability of high diluted homeopathic
medicines to modulate gene expression in cell cultures. In line with these studies, we …

Aging hallmarks and anti-aging strategies: a landscape of research advancement

R Tenchov, J Sasso, X Wang, QA Zhou - 2023 - chemrxiv.org
Aging is a dynamic, time-dependent process characterized by a gradual accumulation of cell
damage. Continual functional decline in the intrinsic ability of living organisms to accurately …

Muscle health in Hispanic women. REDLINC VIII

JE Blümel, C Salinas, L Danckers, K Tserotas… - …, 2020 - Taylor & Francis
Objectives: This study aimed to evaluate muscle strength and related factors in Hispanic
women. Methods: We studied 593 women between 40 and 89 years old. The women were …

[HTML][HTML] Staphylococcus aureus phagocytosis is affected by senescence

E Robledo, PG Benito Rodriguez, IA Vega… - Frontiers in …, 2023 - frontiersin.org
Senescent cells accumulate in multicellular animals with aging, resulting in organ or tissue
dysfunction. These alterations increase the incidence of a variety of illnesses, including …

[HTML][HTML] Chronic senescent human mesenchymal stem cells as possible contributor to the wound healing disorder after exposure to the alkylating agent sulfur mustard

S Rothmiller, N Jäger, N Meier, T Meyer, A Neu… - Archives of …, 2021 - Springer
Wound healing is a complex process, and disturbance of even a single mechanism can
result in chronic ulcers developing after exposure to the alkylating agent sulfur mustard …