Recently drug‐induced senescence has gained momentum as a new approach in cancer
therapy. It is accepted that senescent cells display typical phenotypic features including …

Methods This retrospective study enrolled 82 patients treated for BP at the Department of
Dermatovenereology, University Hospital Center Zagreb from January 2015 to December …

(1) Abdominal aortic aneurysm (AAA) is a silent, progressive disease with significant
mortality from rupture. Whilst screening programmes are now able to detect this pathology …

BACKGROUND: Forkhead box O3 (FOXO3) is a transcription factor that regulates stress
resistance, metabolism, cell cycle, and apoptosis. Several studies exhibited the association …

Hepatic stellate cells (HSCs) are the key effector cells in liver fibrosis. They are the main
producers of excessive amounts of extracellular matrix components during fibrogenesis and …

Sodium-glucose cotransporter 2 inhibitors (SGLT2 inhibitors) have evolved from their initial
role as anti-diabetic drugs to garner recognition for their remarkable cardio-protective and …

Dermal fibroblasts are the main actor in many proteins' secretion, including collagen,
preserving skin function. Free radicals are involved in skin aging and damages involving …

The present study aimed to evaluate the effect of interleukin-22 (IL-22), secreted by cervical
cancer-associated fibroblasts (CAFs), on the senescence of normal fibroblasts (NFs) and the …

Psoriasis is a chronic immune-mediated skin disease in which upper epidermal
keratinocytes exhibit a senescent-like phenotype. In psoriatic skin, a variety of inflammatory …

Феномен клеточного старения впервые был описан как предел деления нормальных
клеток в культуре. С момента первого упоминания и вплоть до недавнего времени …