Expression profiles, biological functions and clinical significance of circRNAs in bladder cancer
X Yang, T Ye, H Liu, P Lv, C Duan, X Wu, K Jiang, H Lu… - Molecular cancer, 2021 - Springer
Circular RNAs (circRNAs), which are single-stranded closed-loop RNA molecules lacking
terminal 5′ caps and 3′ poly (A) tails, are attracting increasing scientific attention for their …
terminal 5′ caps and 3′ poly (A) tails, are attracting increasing scientific attention for their …
The role of N6-methyladenosine (m6A) modification in the regulation of circRNAs
L Zhang, C Hou, C Chen, Y Guo, W Yuan, D Yin, J Liu… - Molecular cancer, 2020 - Springer
Abstract N 6-methyladenosine (m 6 A), the most abundant modification in eukaryotic cells,
regulates RNA transcription, processing, splicing, degradation, and translation. Circular …
regulates RNA transcription, processing, splicing, degradation, and translation. Circular …
Cancer cell-derived exosomal circUHRF1 induces natural killer cell exhaustion and may cause resistance to anti-PD1 therapy in hepatocellular carcinoma
PF Zhang, C Gao, XY Huang, JC Lu, XJ Guo, GM Shi… - Molecular cancer, 2020 - Springer
Objective Natural killer (NK) cells play a critical role in the innate antitumor immune
response. Recently, NK cell dysfunction has been verified in various malignant tumors …
response. Recently, NK cell dysfunction has been verified in various malignant tumors …
The circular RNA circDLG1 promotes gastric cancer progression and anti-PD-1 resistance through the regulation of CXCL12 by sponging miR-141-3p
DL Chen, H Sheng, DS Zhang, Y Jin, BT Zhao… - Molecular Cancer, 2021 - Springer
Abstract Background Dysregulation of circular RNAs (circRNAs) plays an important role in
the development of gastric cancer; thus, revealing the biological and molecular mechanisms …
the development of gastric cancer; thus, revealing the biological and molecular mechanisms …
circRNA-miRNA-mRNA in breast cancer
M Zhang, X Bai, X Zeng, J Liu, F Liu, Z Zhang - Clinica Chimica Acta, 2021 - Elsevier
Among cancers, breast cancer has the highest incidence rate among women and poses a
tremendous threat to women's health. Messenger RNA (mRNA), microRNA (miRNA) and …
tremendous threat to women's health. Messenger RNA (mRNA), microRNA (miRNA) and …
Recent advances of nucleic acid-based cancer biomarkers and biosensors
J Zhao, K Xia, P He, G Wei, X Zhou, X Zhang - Coordination Chemistry …, 2023 - Elsevier
Nucleic acid-based cancer biomarkers (NABCBs) have emerged as a notable and
continuously captivating research focal point within the domain of oncology. As a result …
continuously captivating research focal point within the domain of oncology. As a result …
Circular RNA circSDHC serves as a sponge for miR-127-3p to promote the proliferation and metastasis of renal cell carcinoma via the CDKN3/E2F1 axis
J Cen, Y Liang, Y Huang, Y Pan, G Shu, Z Zheng… - Molecular cancer, 2021 - Springer
Background There is increasing evidence that circular RNAs (circRNAs) have significant
regulatory roles in cancer development and progression; however, the expression patterns …
regulatory roles in cancer development and progression; however, the expression patterns …
Circular RNA: Biogenesis, degradation, functions and potential roles in mediating resistance to anticarcinogens
X Geng, Y Jia, Y Zhang, L Shi, Q Li, A Zang… - Epigenomics, 2020 - Taylor & Francis
Aim: This review aims to systematically describe the biogenesis and degradation of circular
RNAs (circRNAs), discusses the major functions of circRNAs, introduces the mechanisms by …
RNAs (circRNAs), discusses the major functions of circRNAs, introduces the mechanisms by …
[HTML][HTML] circPTCH1 promotes invasion and metastasis in renal cell carcinoma via regulating miR-485-5p/MMP14 axis
H Liu, G Hu, Z Wang, Q Liu, J Zhang, Y Chen… - Theranostics, 2020 - ncbi.nlm.nih.gov
Background: Circular RNAs (circRNAs) are a new class of non-coding RNAs (ncRNAs) that
are derived from exons or introns by special selective shearing. circRNAs have been shown …
are derived from exons or introns by special selective shearing. circRNAs have been shown …
Therapeutic targeting of FUBP3 phase separation by GATA2-AS1 inhibits malate-aspartate shuttle and neuroblastoma progression via modulating SUZ12 activity
X Wang, Y Guo, G Chen, E Fang, J Wang, Q Li, D Li… - Oncogene, 2023 - nature.com
Malate-aspartate shuttle (MAS) is essential for maintaining glycolysis and energy
metabolism in tumors, while its regulatory mechanisms in neuroblastoma (NB), the …
metabolism in tumors, while its regulatory mechanisms in neuroblastoma (NB), the …