The exclusive expression of uromodulin in the kidneys has made it an intriguing protein in
kidney and cardiovascular research. Genome-wide association studies discovered variants …

Race is a social construct, but self-identified Black people are known to have higher
prevalence and worse outcomes of hypertension than White people. This may be partly due …

Uromodulin, also known as the Tamm-Horsfall protein, is predominantly expressed in
epithelial cells of the kidney. It is secreted mainly in the urine, although small amounts are …

Introduction Uromodulin is a kidney-specific tubular protein, and its assessment in serum
(sUMOD) reveals the potential as a novel marker for function and the integrity of renal …

Сhronic kidney Disease (CKD) is the cause of both morbidity and mortality worldwide. In
Ukraine, 12% of the population is diagnosed with CKD. Significantly worsen the quality of …

Uromodulin, also referred to as Tamm Horsfall protein (THP), is a renal protein exclusively
synthesized by the kidneys and represents the predominant urinary protein under normal …

Background Pregnancy involves major adaptations in renal haemodynamics, tubular, and
endocrine functions. Hypertensive disorders of pregnancy are a leading cause of maternal …

Uromodulin is a kidney-specific glycoprotein which is exclusively produced by the epithelial
cells lining the thick ascending limb and early distal convoluted tubule. It is currently …

Background Diabetic nephropathy (DN) is the leading cause of end-stage renal disease.
Exosomes are promising biomarkers for disease diagnosis and uromodulin is a kidney …

Objectives: Hypertension is a common condition worldwide; however, its underlying
mechanisms remain largely unknown. This study aimed to identify urinary peptides …