[HTML][HTML] Diet-gut microbiota-epigenetics in metabolic diseases: From mechanisms to therapeutics
D Li, Y Li, S Yang, J Lu, X Jin, M Wu - Biomedicine & Pharmacotherapy, 2022 - Elsevier
The prevalence of metabolic diseases, including obesity, dyslipidemia, type 2 diabetes
mellitus (T2DM), and non-alcoholic fatty liver disease (NAFLD), is a severe burden in human …
mellitus (T2DM), and non-alcoholic fatty liver disease (NAFLD), is a severe burden in human …
[HTML][HTML] TLR2 and TLR4 in Parkinson's disease pathogenesis: The environment takes a toll on the gut
Parkinson's disease (PD) is an incurable, devastating disorder that is characterized by
pathological protein aggregation and neurodegeneration in the substantia nigra. In recent …
pathological protein aggregation and neurodegeneration in the substantia nigra. In recent …
[HTML][HTML] Butyrate protects mice against methionine–choline-deficient diet-induced non-alcoholic steatohepatitis by improving gut barrier function, attenuating …
Butyrate exerts protective effects against non-alcoholic steatohepatitis (NASH), but the
underlying mechanisms are unclear. We aimed to investigate the role of butyrate-induced …
underlying mechanisms are unclear. We aimed to investigate the role of butyrate-induced …
[HTML][HTML] Impact of the gut microbiome on the genome and epigenome of colon epithelial cells: contributions to colorectal cancer development
J Allen, CL Sears - Genome medicine, 2019 - Springer
In recent years, the number of studies investigating the impact of the gut microbiome in
colorectal cancer (CRC) has risen sharply. As a result, we now know that various microbes …
colorectal cancer (CRC) has risen sharply. As a result, we now know that various microbes …
Anti-senescence compounds: a potential nutraceutical approach to healthy aging
F Gurău, S Baldoni, F Prattichizzo, E Espinosa… - Ageing Research …, 2018 - Elsevier
The desire of eternal youth seems to be as old as mankind. However, the increasing life
expectancy experienced by populations in developed countries also involves a significantly …
expectancy experienced by populations in developed countries also involves a significantly …
Chemoprevention of colorectal cancer by black raspberry anthocyanins involved the modulation of gut microbiota and SFRP2 demethylation
L Chen, B Jiang, C Zhong, J Guo, L Zhang… - …, 2018 - academic.oup.com
Freeze-dried black raspberry (BRB) powder is considered as a potential cancer
chemopreventive agent. In this study, we fed azoxymethane (AOM)/dextran sodium sulfate …
chemopreventive agent. In this study, we fed azoxymethane (AOM)/dextran sodium sulfate …
[HTML][HTML] Organic acids as alternatives for antibiotic growth promoters alter the intestinal structure and microbiota and improve the growth performance in broilers
D Dai, K Qiu, H Zhang, S Wu, Y Han, Y Wu… - Frontiers in …, 2021 - frontiersin.org
The present study aimed to investigate the effects of organic acids (OA) as alternatives for
antibiotic growth promoters (AGP) on growth performance, intestinal structure, as well as …
antibiotic growth promoters (AGP) on growth performance, intestinal structure, as well as …
[HTML][HTML] 27-Hydroxycholesterol contributes to cognitive deficits in APP/PS1 transgenic mice through microbiota dysbiosis and intestinal barrier dysfunction
Y Wang, Y An, W Ma, H Yu, Y Lu, X Zhang… - Journal of …, 2020 - Springer
Background Research on the brain-gut-microbiota axis has led to accumulating interest in
gut microbiota dysbiosis and intestinal barrier dysfunction in Alzheimer's disease (AD). Our …
gut microbiota dysbiosis and intestinal barrier dysfunction in Alzheimer's disease (AD). Our …
Dietary nutrients shape gut microbes and intestinal mucosa via epigenetic modifications
J Wu, Y Zhao, X Wang, L Kong… - Critical reviews in …, 2022 - Taylor & Francis
The imbalance of intestinal microecology firstly impairs intestinal mucosa barrier and
function, then further damages the functions and homeostasis of distal organs, leading to …
function, then further damages the functions and homeostasis of distal organs, leading to …
[HTML][HTML] Secretome of Intestinal Bacilli: A Natural Guard against Pathologies
Current studies of human gut microbiome usually do not consider the special functional role
of transient microbiota, although some of its members remain in the host for a long time and …
of transient microbiota, although some of its members remain in the host for a long time and …