Aging is characterized by systemic chronic inflammation, which is accompanied by cellular
senescence, immunosenescence, organ dysfunction, and age-related diseases. Given the …

Mitochondria play a key role in both health and disease. Their function is not limited to
energy production but serves multiple mechanisms varying from iron and calcium …

Skeletal muscle regeneration depends on the correct expansion of resident quiescent stem
cells (satellite cells), a process that becomes less efficient with aging. Here, we show that …

Huntington's disease is an inherited neurodegenerative disease described 150 years ago
by George Huntington. The genetic defect was identified in 1993 to be an expanded CAG …

Aging accompanied by several age-related complications, is a multifaceted inevitable
biological progression involving various genetic, environmental, and lifestyle factors. The …

A large body of evidence indicates the existence of a complex pathophysiological
relationship between cardiovascular diseases and cancer. Mitochondria are crucial …

Cadmium is one of the environmental and occupational pollutants and its potential adverse
effects on human health have given rise to substantial concern. Cadmium causes damage to …

Stroke is one of the leading causes of death and long-term disability worldwide. More than
80% of strokes are ischemic, caused by an occlusion of cerebral arteries. Without question …

Intestinal metabolism-related diseases, such as constipation, inflammatory bowel disease,
irritable bowel syndrome, and colorectal cancer, could be associated with the dysfunction of …

Mitochondria are centers of energy metabolism. The mitochondrial network is shaped by
mitochondrial dynamics, including the processes of mitochondrial fission and fusion and …