COVID-19 as an acute inflammatory disease
RH Manjili, M Zarei, M Habibi… - The journal of immunology, 2020 - journals.aai.org
Abstract The 2019 coronavirus disease (COVID-19) pandemic caused by the virus severe
acute respiratory syndrome coronavirus-2 (SARS-CoV-2) has created an unprecedented …
acute respiratory syndrome coronavirus-2 (SARS-CoV-2) has created an unprecedented …
Epithelial barrier dysfunction in chronic respiratory diseases
FM Carlier, C de Fays, C Pilette - Frontiers in physiology, 2021 - frontiersin.org
Mucosal surfaces are lined by epithelial cells, which provide a complex and adaptive
module that ensures first-line defense against external toxics, irritants, antigens, and …
module that ensures first-line defense against external toxics, irritants, antigens, and …
[HTML][HTML] Crosstalk of toll-like receptors signaling and Nrf2 pathway for regulation of inflammation
S Mohan, D Gupta - Biomedicine & Pharmacotherapy, 2018 - Elsevier
Inflammation as a second line of defense of innate immunity plays a crucial role in
eliminating invading pathogens (bacteria, viruses, fungi as well as other parasites). The …
eliminating invading pathogens (bacteria, viruses, fungi as well as other parasites). The …
Metal‐based nanoparticles and the immune system: activation, inflammation, and potential applications
YH Luo, LW Chang, P Lin - BioMed research international, 2015 - Wiley Online Library
Nanomaterials, including metal‐based nanoparticles, are used for various biological and
medical applications. However, metals affect immune functions in many animal species …
medical applications. However, metals affect immune functions in many animal species …
Unpuzzling COVID-19: tissue-related signaling pathways associated with SARS-CoV-2 infection and transmission
The highly infective coronavirus disease 19 (COVID-19) is caused by a novel strain of
coronaviruses–the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) …
coronaviruses–the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) …
Redox role of ROS and inflammation in pulmonary diseases
L Zuo, D Wijegunawardana - Lung Inflammation in Health and Disease …, 2021 - Springer
Reactive oxygen species (ROS), either derived from exogenous sources or overproduced
endogenously, can disrupt the body's antioxidant defenses leading to compromised redox …
endogenously, can disrupt the body's antioxidant defenses leading to compromised redox …
TLRs in pulmonary diseases
Toll-like receptors (TLRs) comprise a clan of proteins involved in identification and triggering
a suitable response against pathogenic attacks. As lung is steadily exposed to multiple …
a suitable response against pathogenic attacks. As lung is steadily exposed to multiple …
Kaempferol ameliorates H9N2 swine influenza virus-induced acute lung injury by inactivation of TLR4/MyD88-mediated NF-κB and MAPK signaling pathways
R Zhang, X Ai, Y Duan, M Xue, W He, C Wang… - Biomedicine & …, 2017 - Elsevier
Kaempferol, a very common type of dietary flavonoids, has been found to exert antioxidative
and anti-inflammatory properties. The purpose of our investigation was designed to reveal …
and anti-inflammatory properties. The purpose of our investigation was designed to reveal …
Emerging role of immune cells as drivers of pulmonary fibrosis
The pathogenesis of pulmonary fibrosis, including idiopathic pulmonary fibrosis (IPF) and
other forms of interstitial lung disease, involves a complex interplay of various factors …
other forms of interstitial lung disease, involves a complex interplay of various factors …
Effects of air pollutants on innate immunity: the role of Toll-like receptors and nucleotide-binding oligomerization domain–like receptors
RN Bauer, D Diaz-Sanchez, I Jaspers - Journal of allergy and clinical …, 2012 - Elsevier
Interactions between exposure to ambient air pollutants and respiratory pathogens have
been shown to modify respiratory immune responses. Emerging data suggest key roles for …
been shown to modify respiratory immune responses. Emerging data suggest key roles for …