Lead (Pb) is a highly toxic metal in aquatic environments. Fish are at the top of the food
chain in most aquatic environments, and are the most susceptible to the toxic effects of Pb …

Despite decades of intensive research, the biological mechanisms that causally underlie
depression are still unclear, and therefore the development of novel effective antidepressant …

Inflammation is an adaptive response of the immune system to noxious insults to maintain
homeostasis and restore functionality. The retina is considered an immune-privileged tissue …

Psychological/physical stressors and local tissue damage increase inflammatory proteins in
tissues and blood in humans and animals, in the absence of pathogenic disease. Stress …

Major depressive disorder (MDD) and other mood disorders remain difficult to effectively
treat, and innovative interventions and therapeutic targets are needed. Psychological …

A central and unique aspect of high-grade serous ovarian carcinoma (HGSC) is the
extensive transcoelomic spreading of tumor cell via the peritoneal fluid or malignant ascites …

Protection against cellular stress from various sources, such as nutritional, physical,
pathogenic, or oncogenic, results in the induction of both intrinsic and extrinsic cellular …

There is growing evidence that stress-induced brain cytokines are important in the etiology
of depression and anxiety. Here, we review how the neuroendocrine responses to …

Recent evidence shows divergence between the concentrations of extracellular 70 kDa heat
shock protein [eHSP70] and its intracellular concentrations [iHSP70] in people with type 2 …

Extracellular heat shock proteins (HSP) can activate dendritic cells (DC) and monocytes/
macrophages, and HSP derived from tumor cells have been regarded as potent adjuvant …