High fructose consumption is associated with metabolic disorders including hyperglycemia
and dyslipidemia, in addition to endothelial dysfunction. Naringin, a flavonoid present in …

Hemodynamic dysfunction mainly characterizes pathophysiology of peripheral arterial
disease (PAD) leading to chronic ischemia. Hemodynamic dysfunction is the origin of …

Peripheral arterial disease (PAD) is an atherosclerotic disease that affects a wide range of
the world's population, reaching up to 200 million individuals worldwide. PAD particularly …

Peripheral artery disease (PAD) pathophysiology extends beyond hemodynamics to include
other operating mechanisms, including endothelial dysfunction. Oxidative stress may be …

Our previous study indicated that Casein kinase 2 interacting protein-1 (CKIP-1) could
promote the activation of the nuclear factor E2-related factor 2 (Nrf2)/antioxidant response …

Peripheral artery disease (PAD) affects more than 230 million people worldwide. PAD
patients suffer from reduced quality of life and are at increased risk of vascular complications …

104 Circulation Research July 7, 2017 environments by applying a stress-theoretical model,
with 2 stressors, job strain and effort–reward imbalance. Job strain considers threat to …

Reactive oxygen species (ROS) are closely related with various pathological disorders.
Therefore, real-time detection of ROS is essential for understanding the procedure of …

Peripheral artery disease (PAD) is characterized by the atherosclerotic narrowing of lower
limb vessels, leading to ischemic muscle pain in older persons. Some patients experience …

New Findings What is the central question of this study? What is the degree to which skeletal
muscle mitochondria‐derived reactive oxygen species (ROS) production is linked to …