Large-scale neural recordings call for new insights to link brain and behavior
Neuroscientists today can measure activity from more neurons than ever before, and are
facing the challenge of connecting these brain-wide neural recordings to computation and …
facing the challenge of connecting these brain-wide neural recordings to computation and …
Mechanisms underlying gain modulation in the cortex
KA Ferguson, JA Cardin - Nature Reviews Neuroscience, 2020 - nature.com
Cortical gain regulation allows neurons to respond adaptively to changing inputs. Neural
gain is modulated by internal and external influences, including attentional and arousal …
gain is modulated by internal and external influences, including attentional and arousal …
Spontaneous behaviors drive multidimensional, brainwide activity
INTRODUCTION In the absence of sensory inputs, the brain produces structured patterns of
activity, which can be as large as or larger than sensory-driven activity. Ongoing activity …
activity, which can be as large as or larger than sensory-driven activity. Ongoing activity …
Molecularly targetable cell types in mouse visual cortex have distinguishable prediction error responses
Predictive processing postulates the existence of prediction error neurons in cortex. Neurons
with both negative and positive prediction error response properties have been identified in …
with both negative and positive prediction error response properties have been identified in …
Neuromodulation of brain state and behavior
DA McCormick, DB Nestvogel… - Annual review of …, 2020 - annualreviews.org
Neural activity and behavior are both notoriously variable, with responses differing widely
between repeated presentation of identical stimuli or trials. Recent results in humans and …
between repeated presentation of identical stimuli or trials. Recent results in humans and …
Waking state: rapid variations modulate neural and behavioral responses
The state of the brain and body constantly varies on rapid and slow timescales. These
variations contribute to the apparent noisiness of sensory responses at both the neural and …
variations contribute to the apparent noisiness of sensory responses at both the neural and …
[HTML][HTML] Cortical membrane potential signature of optimal states for sensory signal detection
The neural correlates of optimal states for signal detection task performance are largely
unknown. One hypothesis holds that optimal states exhibit tonically depolarized cortical …
unknown. One hypothesis holds that optimal states exhibit tonically depolarized cortical …
Facemap: a framework for modeling neural activity based on orofacial tracking
Recent studies in mice have shown that orofacial behaviors drive a large fraction of neural
activity across the brain. To understand the nature and function of these signals, we need …
activity across the brain. To understand the nature and function of these signals, we need …
Behavioral decomposition reveals rich encoding structure employed across neocortex in rats
The cortical population code is pervaded by activity patterns evoked by movement, but it
remains largely unknown how such signals relate to natural behavior or how they might …
remains largely unknown how such signals relate to natural behavior or how they might …