Paclitaxel (PTX) is widely used to treat a number of malignancies, although it has toxic side
effects. Hesperidin (HES) has a wide range of biological and pharmacological properties …

Background Drug-induced liver injury (DILI) is the most challenging and thought-provoking
liver problem for hepatologists owing to unregulated medication usage in medical practices …

This study aimed to determine the potential protective effects of chrysin (CHR) on
experimental cadmium (Cd)-induced lung toxicity in rats. To this end, rats were divided into …

Cancer treatment is one of the main challenges of global health. For decades, researchers
have been trying to find anti-cancer compounds with minimal side effects. In recent years …

Abstract Background Cadmium (Cd) is a strong toxic agent and causes serious damage to
testicular tissues. Chrysin (CHR) is a natural flavonoid with many effective properties …

Fluoride and aluminum are ubiquitous toxic metals with adverse reproductive effects. The
citrus flavonoid hesperidin has protective activities but poor solubility and bioavailability …

Abstract Sine oculis homeobox 4 (SIX4), a critical transcription factor modulating organ
development, potentially participates in tumorigenesis through numerous pathways. Here …

For thousands of years, medicinal plants have played a pivotal role in maintaining human
health and improving the quality of human life. This study was designed to analyze the …

Abstract Heat shock protein 27 (Hsp27) is an important member of the chaperone protein
family and its overexpression promotes cancer cell survival. Here, we investigated the …

Objective (s): Oxaliplatin (OXL) is a platinum-based chemotherapeutic agent widely used in
the treatment of colorectal cancer. Unfortunately, this important drug also causes unwanted …