[HTML][HTML] Implications of Porphyromonas gingivalis peptidyl arginine deiminase and gingipain R in human health and diseases

YC Chow, HC Yam, B Gunasekaran, WY Lai… - Frontiers in Cellular …, 2022 - frontiersin.org
Porphyromonas gingivalis is a major pathogenic bacterium involved in the pathogenesis of
periodontitis. Citrullination has been reported as the underlying mechanism of the …

Illuminating the oral microbiome: cellular microbiology

RJ Lamont, DP Miller, J Bagaitkar - FEMS Microbiology …, 2023 - academic.oup.com
Epithelial cells line mucosal surfaces such as in the gingival crevice and provide a barrier to
the ingress of colonizing microorganisms. However, epithelial cells are more than a passive …

[HTML][HTML] Glycation of Host Proteins Increases Pathogenic Potential of Porphyromonas gingivalis

M Śmiga, JW Smalley, P Ślęzak, JL Brown… - International Journal of …, 2021 - mdpi.com
The non-enzymatic addition of glucose (glycation) to circulatory and tissue proteins is a
ubiquitous pathophysiological consequence of hyperglycemia in diabetes. Given the high …

Ultra‐Rapid and Specific Gelation of Collagen Molecules for Transparent and Tough Gels by Transition Metal Complexation

T Suezawa, N Sasaki, Y Yukawa, N Assan… - Advanced …, 2023 - Wiley Online Library
Collagen is the most abundant protein in the human body and one of the main components
of stromal tissues in tumors which have a high elastic modulus of over 50 kPa. Although …

Organotypic model of the gingiva for studying bacterial and viral pathogens implicated in periodontitis

A Golda, A Gasiorek, E Dobosz, Z Oruba… - Journal of Oral …, 2024 - Taylor & Francis
ABSTRACT Background Three-dimensional (3D) tissue models bridge the gap between
conventional two-dimensional cell cultures and animal models. The aim of this study was to …

[HTML][HTML] Cellular memory function from 3D to 2D: Three-dimensional high density collagen microfiber cultures induce their resistance to reactive oxygen species

A Yamada, S Kitano, M Matsusaki - Materials Today Bio, 2024 - Elsevier
Cell properties generally change when the culture condition is changed. However,
mesenchymal stem cells cultured on a hard material surface maintain their differentiation …

[HTML][HTML] SARS-CoV-2, periodontitis and brain inflammation: a putative role in epilepsy and neurological disorders

GWL Tessarin, RM Dos Santos - Frontiers of Oral and …, 2021 - fomm.amegroups.org
COVID-19 was first reported in December 2019 in Wuhan, Hubei Province, China. The
severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2) causes fever, dry cough …