[HTML][HTML] Update on the treatment of type 2 diabetes mellitus

JJ Marín-Peñalver, I Martín-Timón… - World journal of …, 2016 - ncbi.nlm.nih.gov
To achieve good metabolic control in diabetes and keep long term, a combination of
changes in lifestyle and pharmacological treatment is necessary. Achieving near-normal …

Re-exploring promising α-glucosidase inhibitors for potential development into oral anti-diabetic drugs: Finding needle in the haystack

U Ghani - European journal of medicinal chemistry, 2015 - Elsevier
Abstract Treatment of diabetes mellitus by oral α-glucosidase inhibitors is currently confined
to acarbose, miglitol and voglibose marred by efficacy problems and unwanted side effects …

Medicinal plants utilized in Thai Traditional Medicine for diabetes treatment: Ethnobotanical surveys, scientific evidence and phytochemicals

C Andrade, NGM Gomes, S Duangsrisai… - Journal of …, 2020 - Elsevier
Ethnopharmacological relevance Diabetes mellitus remains the most lethal metabolic
disease of contemporaneous times and despite the therapeutic arsenal currently available …

Progress in the discovery of naturally occurring anti-diabetic drugs and in the identification of their molecular targets

JH He, LX Chen, H Li - Fitoterapia, 2019 - Elsevier
Diabetes mellitus (DM), a chronic metabolic disease, severely affects patients' life and
intensively increases risks of developing other diseases. It is estimated that 0.4 billion …

Design and synthesis of sulfonium derivatives: a novel class of α-glucosidase inhibitors with potent in vivo antihyperglycemic activities

L Lu, J Chen, W Tao, Z Wang, D Liu… - Journal of Medicinal …, 2023 - ACS Publications
We report the first attempt of double-spot structural modification on a side-chain moiety of
sulfonium-type α-glucosidase inhibitors isolated from genus Salacia. A series of sulfonium …

Isolated compounds from natural products with potential antidiabetic activity-a systematic review

A Munhoz, TS Frode - Current diabetes reviews, 2018 - ingentaconnect.com
Background: Worldwide, Type 2 diabetes has become a growing health problem. While
many research articles in the field of ethnopharmacology have focused on the antidiabetic …

Synthesis and application of phosphonothioates, phosphonodithioates, phosphorothioates, phosphinothioates and related compounds

DJ Jones, EM O'Leary, TP O'Sullivan - Tetrahedron Letters, 2018 - Elsevier
Synthesis and application of phosphonothioates, phosphonodithioates, phosphorothioates,
phosphinothioates and related compounds - ScienceDirect Skip to main contentSkip to article …

A review of biologically active natural products from a desert plant Cistanche tubulosa

T Morikawa, H Xie, Y Pan, K Ninomiya… - Chemical and …, 2019 - jstage.jst.go.jp
Abstract An Orobanchaceae plant Cistanche tubulosa (SCHENK) WIGHT (Kanka-nikujuyou
in Japanese), which is one of the authorized plant resources as Cistanches Herba in both …

A review of antidiabetic active thiosugar sulfoniums, salacinol and neokotalanol, from plants of the genus Salacia

T Morikawa, K Ninomiya, G Tanabe, H Matsuda… - Journal of natural …, 2021 - Springer
During our studies characterizing functional substances from food resources for the
prevention and treatment of lifestyle-related diseases, we isolated the active constituents …

Sweet selenium: Synthesis and properties of selenium-containing sugars and derivatives

F Mangiavacchi, IF Coelho Dias, I Di Lorenzo, P Grzes… - Pharmaceuticals, 2020 - mdpi.com
In the last decades, organoselenium compounds gained interest due to their important
biological features. However, the lack of solubility, which characterizes most of them, makes …