The lifecycle of skeletal muscle mitochondria in obesity

CA Pileggi, G Parmar, ME Harper - Obesity Reviews, 2021 - Wiley Online Library
Skeletal muscle possesses dramatic metabolic plasticity that allows for the rapid adaptation
in cellular energy transduction to meet the demands of the organism. Obesity elicits changes …

[HTML][HTML] Skeletal muscle quality: a biomarker for assessing physical performance capabilities in young populations

MA Naimo, AN Varanoske, JM Hughes… - Frontiers in …, 2021 - frontiersin.org
Muscle quality (MQ), defined as the amount of strength and/or power per unit of muscle
mass, is a novel index of functional capacity that is increasingly relied upon as a critical …

Muscle memory: myonuclear accretion, maintenance, morphology, and miRNA levels with training and detraining in adult mice

KA Murach, CB Mobley, CJ Zdunek… - Journal of cachexia …, 2020 - Wiley Online Library
Background In the context of mass regulation,'muscle memory'can be defined as long‐
lasting cellular adaptations to hypertrophic exercise training that persist during detraining …

Satellite cell depletion disrupts transcriptional coordination and muscle adaptation to exercise

DA Englund, VC Figueiredo, CM Dungan, KA Murach… - Function, 2021 - academic.oup.com
Satellite cells are required for postnatal development, skeletal muscle regeneration across
the lifespan, and skeletal muscle hypertrophy prior to maturity. Our group has aimed to …

[HTML][HTML] Muscle hypertrophy and muscle strength: dependent or independent variables? A provocative review

C Reggiani, S Schiaffino - European journal of translational …, 2020 - ncbi.nlm.nih.gov
The question whether the muscle hypertrophy induced by resistance training, hormone
administration or genetic manipulation is accompanied by a proportional increase in muscle …

Muscle-specific cellular and molecular adaptations to late-life voluntary concurrent exercise

CM Dungan, CR Brightwell, Y Wen, CJ Zdunek… - Function, 2022 - academic.oup.com
Murine exercise models can provide information on factors that influence muscle
adaptability with aging, but few translatable solutions exist. Progressive weighted wheel …

[HTML][HTML] Role of damage and management in muscle hypertrophy: different behaviors of muscle stem cells in regeneration and hypertrophy

S Fukada, T Akimoto, A Sotiropoulos - Biochimica et Biophysica Acta (BBA) …, 2020 - Elsevier
Skeletal muscle is a dynamic tissue with two unique abilities; one is its excellent
regenerative ability, due to the activity of skeletal muscle–resident stem cells named muscle …

Adaptation of the transcriptional response to resistance exercise over 4 weeks of daily training

MR Viggars, H Sutherland, H Lanmüller… - Faseb …, 2022 - researchonline.ljmu.ac.uk
We present the time course of change in the muscle transcriptome 1 h after the last exercise
bout of a daily resistance training program lasting 2, 10, 20, or 30 days. Daily exercise in rat …

Making mice mighty: recent advances in translational models of load-induced muscle hypertrophy

KA Murach, JJ McCarthy… - Journal of Applied …, 2020 - journals.physiology.org
The ability to genetically manipulate mice allows for gain-and loss-of-function in vivo,
making them an ideal model for elucidating mechanisms of skeletal muscle mass regulation …

Resistance training attenuates activation of STAT3 and muscle atrophy in tumor-bearing mice

MTJ Testa, PS Cella, PC Marinello… - Frontiers in …, 2022 - frontiersin.org
Purpose Although the role of signal transducers and activators of transcription (STAT3) in
cachexia due to the association of circulating IL-6 and muscle wasting has been extensively …