Antibiotic resistance in Enterobacteriaceae: mechanisms and clinical implications

J Iredell, J Brown, K Tagg - Bmj, 2016 - bmj.com
Resistance of the Enterobacteriaceae to antibiotics, especially of the β lactam type, is
increasingly dominated by the mobilization of continuously expressed single genes that …

Antifungal drug resistance: mechanisms, epidemiology, and consequences for treatment

MA Pfaller - The American journal of medicine, 2012 - Elsevier
Antifungal resistance continues to grow and evolve and complicate patient management,
despite the introduction of new antifungal agents. In vitro susceptibility testing is often used …

Extensive impact of non-antibiotic drugs on human gut bacteria

L Maier, M Pruteanu, M Kuhn, G Zeller, A Telzerow… - Nature, 2018 - nature.com
A few commonly used non-antibiotic drugs have recently been associated with changes in
gut microbiome composition, but the extent of this phenomenon is unknown. Here, we …

EUCAST rapid antimicrobial susceptibility testing (RAST) in blood cultures: validation in 55 European laboratories

A Åkerlund, E Jonasson, E Matuschek… - Journal of …, 2020 - academic.oup.com
Objectives When bloodstream infections are caused by resistant bacteria, rapid
antimicrobial susceptibility testing (RAST) is important for adjustment of therapy. The …

Epidemiology, clinical presentation, laboratory diagnosis, antimicrobial resistance, and antimicrobial management of invasive Salmonella infections

JA Crump, M Sjölund-Karlsson… - Clinical microbiology …, 2015 - Am Soc Microbiol
Salmonella enterica infections are common causes of bloodstream infection in low-resource
areas, where they may be difficult to distinguish from other febrile illnesses and may be …

Acinetobacter baumannii: Emergence of a Successful Pathogen

AY Peleg, H Seifert, DL Paterson - Clinical microbiology reviews, 2008 - Am Soc Microbiol
Acinetobacter baumannii has emerged as a highly troublesome pathogen for many
institutions globally. As a consequence of its immense ability to acquire or upregulate …

Antimicrobial activity and resistance: influencing factors

J Li, S Xie, S Ahmed, F Wang, Y Gu, C Zhang… - Frontiers in …, 2017 - frontiersin.org
Rational use of antibiotic is the key approach to improve the antibiotic performance and
tackling of the antimicrobial resistance. The efficacy of antimicrobials are influenced by many …

Framework for optimisation of the clinical use of colistin and polymyxin B: the Prato polymyxin consensus

RL Nation, J Li, O Cars, W Couet… - The Lancet infectious …, 2015 - thelancet.com
In the face of diminishing therapeutic options for the treatment of infections caused by
multidrug-resistant, Gram-negative bacteria, clinicians are increasingly using colistin and …

Emerging applications of machine learning in food safety

X Deng, S Cao, AL Horn - Annual Review of Food Science and …, 2021 - annualreviews.org
Food safety continues to threaten public health. Machine learning holds potential in
leveraging large, emerging data sets to improve the safety of the food supply and mitigate …

Rapid pathogen-specific phenotypic antibiotic susceptibility testing using digital LAMP quantification in clinical samples

NG Schoepp, TS Schlappi, MS Curtis… - Science translational …, 2017 - science.org
Rapid antimicrobial susceptibility testing (AST) is urgently needed for informing treatment
decisions and preventing the spread of antimicrobial resistance resulting from the misuse …