Chronic pancreatitis (CP) is a chronic inflammatory and fibrotic disease of the pancreas. The
incidence of CP is increasing worldwide but the effective therapies are lacking. Hence, it is …

Aims This study measured the effects of 5-Fluorouracil (5-FU), calcitriol (VD 3), and/or
thymoquinone (TQ) single/dual/triple therapies on cell cycle progression, apoptosis …

Simple Summary Failure of chemotherapy is common during the treatment of colon cancer,
and there is a compelling need to develop alternative therapeutic approaches against this …

Although ovarian sex steroids could have protective roles against colorectal cancer (CRC) in
women, little is currently known about their potential anti-tumorigenic effects in men. Hence …

Colorectal cancer (CRC) is the third most common malignancy worldwide and the second
most deadly cancer. Scientists have projected that by 2040, the prevalence will reach up to …

Recent epidemiological and preclinical evidence indicates that vitamin D3 inhibits colorectal
cancer (CRC) progression, but the mechanism has not been completely elucidated. This …

Introduction Although the synthetic vitamin D analogue, Paricalcitol, and omega-3 Fatty
acids (ω-3) alleviated diabetic nephropathy (DN), their combination was not previously …

Background Chronic iron overload could induce nephropathy via oxidative stress and
inflammation, and chelating therapy has limited efficacy in removing excess intracellular …

This study explored the roles of activins and follistatin in colorectal cancers. Paired
malignant and normal colonic tissues were collected from archived paraffin-embedded (n …

1Department of Medical Biology, Pomeranian Medical University, Szczecin, Poland; 2Liver
and Internal Medicine Unit, Medical University of Warsaw, Warsaw, Poland; 3Translational …