Iodothyronine deiodinases (DIO) are a family of selenoproteins controlling systemic and
local availability of the major thyroid hormone l-thyroxine (T4), a prohormone secreted by the …

Thousands of natural or manufactured chemicals were defined as endocrine-disrupting
chemicals (EDCs) because they can interfere with hormone activity and the endocrine …

Food contact materials (FCMs) and food contact articles are ubiquitous in today's globalized
food system. Chemicals migrate from FCMs into foodstuffs, so called food contact chemicals …

We are all exposed to endocrine-disrupting chemicals (EDCs) starting from embryonic life.
The fetus and child set up crucial developmental processes allowing adaptation to the …

Synthetic chemicals with endocrine disrupting properties are pervasive in the environment
and are present in the bodies of humans and wildlife. As thyroid hormones (THs) control …

Everyday use chemicals have been demonstrated to be endocrine disruptors. Since normal
thyroid function during pregnancy is transcendental for the neurodevelopment of the …

The thyroid hormone system is a main target of endocrine disruptor compounds (EDC) at all
levels of its intricately fine-tuned feedback regulation, synthesis, distribution, metabolism and …

A number of xenobiotics interfere with thyroid hormone (TH) signaling. Although adequate
supplies of TH are necessary for normal brain development, regulatory reliance on serum …

Endocrine disrupting chemicals (EDCs) are ubiquitous in the environment and involve
diverse chemical-receptor interactions that can perturb hormone signaling. The Organization …

Purpose Iodine is an essential micronutrient required for thyroid hormone biosynthesis.
However, overtreatment with iodine can unfavorably affect thyroid physiology. The aim of …