Anti-angiogenic therapies (AATs) are used to treat different types of cancers. However, their
success is limited owing to insufficient efficacy and resistance. Recently, single-cell omics …

Growth of new blood vessels is considered requisite to cancer progression. Recent findings
revealed that in addition to inducing angiogenesis, tumor-derived factors alter endothelial …

Vascular endothelial cells (ECs) that constitute the inner surface of blood vessels are
essential for new vessel formation and organ homeostasis. ECs display remarkable …

Endothelial cells (ECs) line the luminal surface of blood vessels and play a major role in
vascular (patho)-physiology by acting as a barrier, sensing circulating factors and …

Trauma-induced coagulopathy (TIC) is a major cause of morbidity and mortality in patients
with traumatic injury. It describes the spectrum of coagulation abnormalities that occur …

The blood–brain barrier (BBB) is part of a neurovascular structure located in the brain's
micro vessels, that is essential to maintain brain homeostasis, but prevents the brain uptake …

Major adverse cardiovascular events occurring upon coronary artery bypass graft surgery
are typically accompanied by endothelial dysfunction. Total arterial revascularisation, which …

Single cell technologies, lineage tracing mouse models and advanced imaging techniques
unequivocally improved the resolution of the cellular landscape of atherosclerosis. Although …

In the last decades, it has become evident that endothelial cells (ECs) in the
microvasculature play an important role in the pathophysiology of sepsis-associated multiple …

Vascular endothelial cell (EC) aging has a strong impact on tissue perfusion and overall
cardiovascular health. While studies confined to the investigation of aging-associated …