The cannabis derivative marijuana is the most widely used recreational drug in the Western
world and is consumed by an estimated 83 million individuals (∼ 3% of the world …

Obesity currently represents a major societal and health challenge worldwide. Its prevalence
has reached epidemic proportions and trends continue to rise, reflecting the need for more …

Endocannabinoid signalling is considered one of the most important modulatory systems in
a whole organism. Research has yielded great insight on the mechanisms that link …

The endocannabinoid system is involved in a wide range of processes including the control
of energy acquisition and expenditure. Endocannabinoids and their receptors are present in …

The cannabinoid 1 (CB1) receptor regulates appetite and body weight; however, unwanted
central side effects of both agonists (in wasting disorders) or antagonists (in obesity and …

The gut barrier provides protection from pathogens and its function is compromised in diet-
induced obesity (DIO). The endocannabinoid system in the gut is dysregulated in DIO and …

Objective Consumption of energy‐dense palatable “comfort” food can alleviate stress and
negative emotions, while abrupt withdrawal from a palatable diet can worsen these …

Simple Summary Dysbiosis, which is an imbalance of gut microbial composition and
function, can be caused by several external as well as internal factors, contributing to the …

Obesity is a complex disorder, and the number of people affected is growing every day. In
recent years, research has confirmed the hypothesis that food addiction is a determining …

The latest years have witnessed a growing interest towards the relationship between
neuropsychiatric disease in children with autism spectrum disorders (ASD) and severe …