Nucleic acids are a promising type of therapeutic for the treatment of a wide range of
conditions, including cancer, but they also pose many delivery challenges. For efficient and …

Combination therapy for the treatment of cancer is becoming more popular because it
generates synergistic anticancer effects, reduces individual drug-related toxicity and …

Cancer often develops multidrug resistance (MDR) when cancer cells become resistant to
numerous structurally and functionally different chemotherapeutic agents. MDR is …

The theranostic term is a revolutionary topic in cancer treatment, combining therapeutic and
diagnostic. Theranostic provides an opportunity for diagnosis and response assessment …

Short interfering RNAs (siRNAs), as small non-coding RNA fragments, are one of the widely
studied RNAi inducers for gene modulations. The reasonably designed siRNA probes …

Anticancer drug resistance almost invariably emerges and poses major obstacles towards
curative therapy of various human malignancies. In the current review we will distinguish …

Paclitaxel is one of the most effective chemotherapeutic drugs ever developed and is active
against a broad range of cancers, such as lung, ovarian, and breast cancers. Due to its low …

Glioblastoma multiforme, a grade IV glioma, is the most frequently occurring and invasive
primary tumor of the central nervous system, which causes about 4% of cancer-associated …

Abstract Poly-ε-caprolactone (PCL) has been the subject of extensive research in the past
few years. It is widely explored in drug delivery, where the development of nanomedicines …

There are two main mechanisms by which cells become multidrug resistant (MDR): by
increasing drug efflux pumps on the cell membrane and by increasing anti-apoptotic …