Iron metabolism and tumor biology are intimately linked. Iron facilitates the production of
oxygen radicals, which may either result in iron-induced cell death, ferroptosis, or contribute …

Iron deficiency anaemia is a critical condition in pregnancy which may not easily be
predicted. It has caused a lot of havocs to the mothers and the babies. A widespread health …

Polycythemia vera (PV) is a chronic myeloproliferative neoplasm. Virtually all PV patients
are iron deficient at presentation and/or during the course of their disease. The co-existence …

Iron deficiency anaemia is a global health problem, which particularly affects pregnant
women. Iron deficiency anaemia during pregnancy is associated with increased maternal …

Rationale: Iron deficiency, in the absence of anemia, is common in patients with idiopathic
and heritable pulmonary arterial hypertension (PAH) and is associated with a worse clinical …

A strong mechanistic link between the regulation of iron homeostasis and oxygen sensing is
evident in the lung, where both systems must be properly controlled to maintain lung …

Pulmonary arterial hypertension (PAH) is a pulmonary vasculopathy that causes right
ventricular dysfunction and exercise limitation and progresses to death. New findings from …

Iron deficiency augments hypoxic pulmonary arterial pressure in healthy individuals and
exacerbates pulmonary arterial hypertension (PAH) in patients, even without anemia …

Chronic obstructive pulmonary disease (COPD) is a debilitating inflammatory lung disease
and the third leading cause of death worldwide (1). COPD is characterized by three major …

Anaemia is a highly prevalent condition, which negatively impacts on patients'
cardiovascular performance and quality of life. Anaemia is mainly caused by disturbances of …