Erythroblasts possess unique characteristics as they undergo differentiation from
hematopoietic stem cells. During terminal erythropoiesis, these cells incorporate large …

Non-anaemic iron deficiency (NAID) is a strategic target in cardiovascular medicine because
of its association with a range of adverse effects in various conditions. Endeavours to tackle …

Iron-restricted human anemias are associated with the acquisition of marrow resistance to
the hematopoietic cytokine erythropoietin (Epo). Regulation of Epo responsiveness by iron …

Hepcidin mimetics in polycythemia vera: resolving the irony... : Current Opinion in Hematology
Hepcidin mimetics in polycythemia vera: resolving the irony of iron deficiency and erythrocytosis …

In lung vascular cells, mitochondria serve a canonical metabolic role, governing energy
homeostasis. In addition, mitochondria exist in dynamic networks, which serve noncanonical …

Aims Whether and how iron deficiency (ID) impacts patients with heart failure (HF) with
preserved ejection fraction (HFpEF) remain unclear. The aim of our study was to investigate …

The unique property of the pulmonary circulation to constrict in response to hypoxia, rather
than dilate, brings advantages in both health and disease. Hypoxic pulmonary …

Iron deficiency impairs skeletal muscle metabolism. The underlying mechanisms are
incompletely characterised, but animal and human experiments suggest the involvement of …

Key points Iron acts as a cofactor in the stabilization of the hypoxic‐inducible factor family,
and plays an influential role in the modulation of hypoxic pulmonary vasoconstriction. It is …

Pulmonary hypertension (PH) is an enigmatic vascular disorder characterized by pulmonary
vascular remodeling and increased pulmonary vascular resistance, ultimately resulting in …