Spinal cord injury: molecular mechanisms and therapeutic interventions
X Hu, W Xu, Y Ren, Z Wang, X He, R Huang… - Signal transduction and …, 2023 - nature.com
Spinal cord injury (SCI) remains a severe condition with an extremely high disability rate.
The challenges of SCI repair include its complex pathological mechanisms and the …
The challenges of SCI repair include its complex pathological mechanisms and the …
Electrical stimulation for the treatment of spinal cord injuries: A review of the cellular and molecular mechanisms that drive functional improvements
Spinal cord injury (SCI) is a devastating condition that causes severe loss of motor, sensory
and autonomic functions. Additionally, many individuals experience chronic neuropathic …
and autonomic functions. Additionally, many individuals experience chronic neuropathic …
Pathophysiology and therapeutic approaches for spinal cord injury
Spinal cord injury (SCI) is a disabling condition that disrupts motor, sensory, and autonomic
functions. Despite extensive research in the last decades, SCI continues to be a global …
functions. Despite extensive research in the last decades, SCI continues to be a global …
A comprehensive look at the psychoneuroimmunoendocrinology of spinal cord injury and its progression: mechanisms and clinical opportunities
MA Ortega, O Fraile-Martinez, C García-Montero… - Military Medical …, 2023 - Springer
Spinal cord injury (SCI) is a devastating and disabling medical condition generally caused
by a traumatic event (primary injury). This initial trauma is accompanied by a set of biological …
by a traumatic event (primary injury). This initial trauma is accompanied by a set of biological …
Immune response after central nervous system injury
AFM Salvador, J Kipnis - Seminars in immunology, 2022 - Elsevier
Traumatic injuries of the central nervous system (CNS) affect millions of people worldwide,
and they can lead to severely damaging consequences such as permanent disability and …
and they can lead to severely damaging consequences such as permanent disability and …
Fibrotic scar after spinal cord injury: crosstalk with other cells, cellular origin, function, and mechanism
Z Li, S Yu, X Hu, Y Li, X You, D Tian… - Frontiers in cellular …, 2021 - frontiersin.org
The failure of axonal regeneration after spinal cord injury (SCI) results in permanent loss of
sensorimotor function. The persistent presence of scar tissue, mainly fibrotic scar and …
sensorimotor function. The persistent presence of scar tissue, mainly fibrotic scar and …
Regulatory role of mesenchymal stem cells on secondary inflammation in spinal cord injury
QM Pang, SY Chen, SP Fu, H Zhou… - Journal of …, 2022 - Taylor & Francis
Spinal cord injury (SCI) is a catastrophic condition with high morbidity and mortality that still
lacks effective therapeutic strategies. It is well known that the most important stage in SCI …
lacks effective therapeutic strategies. It is well known that the most important stage in SCI …
The leaky gut and the gut microbiome in sepsis–targets in research and treatment
W Chancharoenthana, S Kamolratanakul… - Clinical …, 2023 - portlandpress.com
Both a leaky gut (a barrier defect of the intestinal surface) and gut dysbiosis (a change in the
intestinal microbial population) are intrinsic to sepsis. While sepsis itself can cause …
intestinal microbial population) are intrinsic to sepsis. While sepsis itself can cause …
The immune microenvironment and tissue engineering strategies for spinal cord regeneration
Y Feng, Y Peng, J Jie, Y Yang, P Yang - Frontiers in Cellular …, 2022 - frontiersin.org
Regeneration of neural tissue is limited following spinal cord injury (SCI). Successful
regeneration of injured nerves requires the intrinsic regenerative capability of the neurons …
regeneration of injured nerves requires the intrinsic regenerative capability of the neurons …
An emerging role of inflammasomes in spinal cord injury and spinal cord tumor
J Chen, Y Shen, X Shao, W Wu - Frontiers in Immunology, 2023 - frontiersin.org
Spinal cord injury (SCI) and spinal cord tumor are devastating events causing structural and
functional impairment of the spinal cord and resulting in high morbidity and mortality; these …
functional impairment of the spinal cord and resulting in high morbidity and mortality; these …